TFB1M and VEGFB

		TFB1M	VEGFB
Description		transcription factor B1, mitochondrial	vascular endothelial growth factor B
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GO Annotations	Cellular Component	Mitochondrial Matrix Mitochondrial Nucleoid	Extracellular Region Extracellular Space Membrane Platelet Alpha Granule Lumen
	Molecular Function	RRNA (adenine-N6,N6-)-dimethyltransferase Activity DNA Binding RNA Binding Protein Binding Mitochondrial Transcription Factor Activity	Vascular Endothelial Growth Factor Receptor Binding Protein Binding Growth Factor Activity Heparin Binding Chemoattractant Activity Identical Protein Binding Vascular Endothelial Growth Factor Receptor 1 Binding
	Biological Process	RRNA Modification Transcription Initiation From Mitochondrial Promoter RRNA Methylation	Response To Hypoxia Positive Regulation Of Protein Phosphorylation Positive Regulation Of Endothelial Cell Proliferation Sprouting Angiogenesis Protein O-linked Glycosylation Response To Xenobiotic Stimulus Vascular Endothelial Growth Factor Signaling Pathway Positive Regulation Of Angiogenesis Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Chemotaxis Induction Of Positive Chemotaxis Positive Regulation Of Cell Division Cardiac Muscle Contraction Positive Regulation Of Mast Cell Chemotaxis Coronary Vasculature Development
Pathways		Transcriptional activation of mitochondrial biogenesis rRNA modification in the mitochondrion	Platelet degranulation VEGF ligand-receptor interactions VEGF binds to VEGFR leading to receptor dimerization
Drugs			Aflibercept
Diseases
GWAS		Dimensional psychopathology (Arousal) ( 29496196) Dimensional psychopathology (Negative) ( 29496196) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Metabolite levels ( 23823483) Waist-hip ratio ( 28552196) Waist-to-hip ratio adjusted for BMI ( 28552196)	Apolipoprotein A1 levels ( 32203549) Body shape index ( 34021172) Crohn's disease ( 28067908) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Fruit consumption ( 32066663) HDL cholesterol levels ( 32203549) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Red blood cell count ( 32888494) Triglyceride levels ( 32203549) Triglycerides ( 30275531) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for body mass index ( 25673412)
Interacting Genes		3 interacting genes: POLRMT TFAM VEGFB	11 interacting genes: ADRB2 FLT1 FOSL1 KLHL12 NRP1 SF1 TFB1M TNXB UCP2 UCP3 VEGFA
Entrez ID		51106	7423
HPRD ID		09515	03237
Ensembl ID		ENSG00000029639	ENSG00000173511
Uniprot IDs		E5KTM5 Q8WVM0	P49765 Q7LAP4
PDB IDs		6AAX 6AJK	2C7W 2VWE 2XAC
Enriched GO Terms of Interacting Partners?
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