PLLP and TRIM59

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PLLP	TRIM59
Description		plasmolipin	tripartite motif containing 59
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Compact Myelin Membrane Raft	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Intraciliary Transport Particle B
	Molecular Function	Protein Binding Structural Constituent Of Myelin Sheath	Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Ion Transport Response To Wounding Myelination	Protein Ubiquitination Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Negative Regulation Of Viral Entry Into Host Cell
Pathways
Drugs
Diseases
GWAS		HDL cholesterol levels ( 32203549) Hip circumference adjusted for BMI ( 28552196) Sleep duration ( 23728906) Systemic lupus erythematosus ( 28714469)	Alanine aminotransferase levels ( 33547301) Alcohol use disorder (total score) ( 30336701) Aspartate aminotransferase levels ( 33547301) Bipolar disorder ( 31043756) Eosinophil percentage of white cells ( 32888494) Intrinsic epigenetic age acceleration ( 29374233) Malaria ( 31844061) Pulse pressure ( 30578418) Systolic blood pressure ( 30578418)
Interacting Genes		52 interacting genes: AQP6 BCL2L13 CCR2 CD164L2 CLDN14 CLEC12B CLEC2D CRB3 CREB3 CYSRT1 DRD2 EBP ELOVL4 ERGIC3 FAM174A FNDC9 FRS3 GOLT1A GPR35 GPX8 GRN HOXA1 HTR2B KCNJ6 KRT34 KRTAP10-1 KRTAP9-2 LHFPL5 LMNA MC4R MFF MMP14 MS4A12 OPRL1 PACC1 PGRMC2 PTAFR RNF122 SAR1A SLC10A6 STING1 SYPL2 TIGIT TMEM14B TMEM167B TMEM174 TMPPE TMPRSS2 TNFSF14 TRIM59 VMA21 ZDHHC15	28 interacting genes: ANKRD33 BLZF1 CCDC33 CDK5 CLDN4 ECSIT EIF2B1 ESR1 ESR2 KRTAP13-3 MACROH2A1 MEI4 MRPL12 NECAB2 NRM OTOL1 PIN1 PLLP PPM1L RASSF3 RHOU SEC22A SNAP47 UBE2J2 UBE2W VTI1B ZDHHC21 ZDHHC22
Entrez ID		51090	286827
HPRD ID		11854	15568
Ensembl ID		ENSG00000102934	ENSG00000213186
Uniprot IDs		A0A024R6T3 Q9Y342	Q8IWR1
PDB IDs
Enriched GO Terms of Interacting Partners?
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