POLR1D and DNAJB4

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		POLR1D	DNAJB4
Description		RNA polymerase I and III subunit D	DnaJ heat shock protein family (Hsp40) member B4
Image			No pdb structure
GO Annotations	Cellular Component	RNA Polymerase III Complex RNA Polymerase I Complex	Nucleoplasm Cytosol Plasma Membrane
	Molecular Function	DNA Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Protein Dimerization Activity	ATPase Activator Activity Protein Binding Unfolded Protein Binding Chaperone Binding
	Biological Process	Transcription, DNA-templated	Response To Unfolded Protein Response To Heat Regulation Of Catalytic Activity Chaperone Cofactor-dependent Protein Refolding
Pathways		Cytosolic sensors of pathogen-associated DNA NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase III Chain Elongation RNA Polymerase I Transcription Termination RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
GWAS		Body mass index ( 26426971)	Adult body size ( 32376654) Body mass index ( 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Body size at age 10 ( 32376654) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cutaneous melanoma or hair colour ( 32341527) Diastolic blood pressure ( 30224653) Liver enzyme levels (alkaline phosphatase) ( 33972514) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Waist circumference ( 25673412)
Interacting Genes		14 interacting genes: CDC25A CRKL DDIT3 DNAJB4 DNAJB6 E2F4 GRB2 HAX1 MAGEA11 MRPL12 NFKBIB NR3C1 POLR1C PXN	10 interacting genes: HSPA6 MDM2 OPRM1 PABPN1 POLR1D RUVBL2 SDIM1 SMAD3 TBL1X TBPL2
Entrez ID		51082	11080
HPRD ID		17877	07486
Ensembl ID		ENSG00000186184	ENSG00000162616
Uniprot IDs		A0A087WTY1 P0DPB5 P0DPB6	B4DNN2 Q9UDY4
PDB IDs		7A6H 7AE1 7AE3 7AEA 7AST 7D58 7D59
Enriched GO Terms of Interacting Partners?
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