PCM1 and DDX23

Number of citations of the paper that reports this interaction (PubMedID 30217970)
5

Data Source:
BioGRID (two hybrid)

		PCM1	DDX23
Description		pericentriolar material 1	DEAD-box helicase 23
Image
GO Annotations	Cellular Component	Pericentriolar Material Cytoplasm Centrosome Centriole Cytosol Membrane Nuclear Membrane Protein-containing Complex Centriolar Satellite Ciliary Transition Zone Ciliary Basal Body Apical Part Of Cell Non-motile Cilium	Chromatin Nucleus Nucleoplasm U5 SnRNP Nucleolus U4/U6 X U5 Tri-snRNP Complex Extracellular Exosome Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding Identical Protein Binding	RNA Binding RNA Helicase Activity Helicase Activity Protein Binding ATP Binding ATP Hydrolysis Activity
	Biological Process	Neuron Migration Centrosome Cycle Interkinetic Nuclear Migration Cytoplasmic Microtubule Organization Microtubule Anchoring Microtubule Anchoring At Centrosome Social Behavior Intraciliary Transport Involved In Cilium Assembly Negative Regulation Of Neurogenesis Cilium Assembly Protein Localization To Centrosome Positive Regulation Of Intracellular Protein Transport Neuronal Stem Cell Population Maintenance Non-motile Cilium Assembly	Cis Assembly Of Pre-catalytic Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Splicing R-loop Disassembly
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2	mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS		Atrial fibrillation ( 28416818) Economic and political preferences ( 22566634) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Triglyceride levels ( 32203549) Waist-hip ratio ( 30108283) Weight ( 28552196)	Bipolar disorder ( 21926972)
Interacting Genes		47 interacting genes: ABI1 ABI2 AKAP9 BBS4 CASK CCDC172 CCHCR1 CDC42 CEP72 CYTH4 DDIT3 DDX23 DPYSL2 DYNLL1 E2F4 ECPAS EPS8 EXOC8 FAM81A FGF20 FXR2 GABARAP GOLGA2 HAP1 ING5 KLC1 KLC4 KRT15 KRT19 KRT24 MCRS1 NECAB2 PCNT PDGFRL PRC1 PRKCI PXN RALBP1 RBM5 RINT1 RPA2 TFIP11 TNFRSF10B TTC8 WASHC3 YWHAE YWHAQ	25 interacting genes: ERG MIR106B MIR128-1 MIR138-2 MIR141 MIR143 MIR19B2 MIR200B MIR200C MIR214 MIR25 MIR363 MIR429 MIR7-1 MIR7-2 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7E MIRLET7G MIRLET7I PCM1 TERF1 TERF2IP WBP4
Entrez ID		5108	9416
HPRD ID		02624	09908
Ensembl ID		ENSG00000078674	ENSG00000174243
Uniprot IDs		A2RUU9 B9EIS5 Q15154	A0A024R0Z3 B3KY11 Q9BUQ8
PDB IDs		6HYL 6HYM	3JCR 4NHO 6AH0 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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