PCDH9 and CYSLTR2

Number of citations of the paper that reports this interaction (PubMedID 28298427)
23

Data Source:
BioGRID (two hybrid)

		PCDH9	CYSLTR2
Description		protocadherin 9	cysteinyl leukotriene receptor 2
Image			No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane Growth Cone Cell-cell Contact Zone	Cellular_component Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Calcium Ion Binding	Cysteinyl Leukotriene Receptor Activity Leukotriene Receptor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding G Protein-coupled Peptide Receptor Activity
	Biological Process	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Forebrain Development	Immune Response Neuropeptide Signaling Pathway Regulation Of Catalytic Activity Leukotriene Signaling Pathway Cellular Response To Glucagon Stimulus
Pathways			Glucagon signaling in metabolic regulation Leukotriene receptors G alpha (q) signalling events G alpha (s) signalling events Glucagon-type ligand receptors ADORA2B mediated anti-inflammatory cytokines production LTC4-CYSLTR mediated IL4 production
Drugs			Nedocromil Leukotriene C4 Leukotriene D4
Diseases
GWAS		Adult body size ( 32376654) Age at first birth ( 34211149) Blood protein levels ( 30072576) Body size at age 10 ( 32376654) Chronotype ( 30696823) Clostridioides difficle infection ( 33841421) Current cigarettes per day in chronic obstructive pulmonary disease ( 29631575) Dental caries ( 23064961) Feeling nervous ( 29500382) Forced expiratory volume in 1 second (occupational environmental exposures interaction) ( 25979521) Gastroesophageal reflux disease ( 34187846) General factor of neuroticism ( 30867560) Insomnia ( 29520036) Itch intensity from mosquito bite ( 28199695) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Latent naming speed ( 30995994) Major depressive disorder ( 27479909) Male fertility ( 22633400) Metabolite levels ( 23823483) Obesity ( 21552555) Photic sneeze reflex ( 27182965) Postoperative survival time in hepatocellular carcinoma ( 30945673 30945699) Pulmonary function decline ( 22424883) Recalcitrant atopic dermatitis ( 25935106) Refractive error ( 32231278) Response to platinum-based chemotherapy (cisplatin) ( 21844884) Sense of smell ( 26632684) Smoking initiation ( 33082346) Smoking status (ever vs never smokers) ( 30643258)	3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Post bronchodilator FEV1/FVC ratio ( 26634245) Response to inhaled corticosteroid treatment in asthma (change in FEV1) ( 24792382) Systemic juvenile idiopathic arthritis ( 27927641)
Interacting Genes		3 interacting genes: CYSLTR2 HTR2A MEOX2	19 interacting genes: ATP5MC2 DBI ENO1 GNAS GRIK1 HSP90B1 KRTAP1-1 LNX1 MTUS2 NCKIPSD PCDH9 PCMT1 RNASEK RNF144A RTN4 SVOP TTC19 YIPF6 YWHAE
Entrez ID		5101	57105
HPRD ID		04661	09293
Ensembl ID		ENSG00000184226	ENSG00000152207
Uniprot IDs		A7E2D9 B7ZM79 Q5VT82 Q9HC56 X5D7N0	A4ZKH2 Q5KU17 Q9NS75
PDB IDs		2EE0
Enriched GO Terms of Interacting Partners?
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