PDE11A and FKBP7

		PDE11A	FKBP7
Description		phosphodiesterase 11A	FKBP prolyl isomerase 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytosol	Endoplasmic Reticulum Endoplasmic Reticulum Lumen
	Molecular Function	Cyclic-nucleotide Phosphodiesterase Activity 3',5'-cyclic-nucleotide Phosphodiesterase Activity 3',5'-cyclic-AMP Phosphodiesterase Activity CGMP-stimulated Cyclic-nucleotide Phosphodiesterase Activity CGMP Binding Metal Ion Binding 3',5'-cyclic-GMP Phosphodiesterase Activity	Peptidyl-prolyl Cis-trans Isomerase Activity Calcium Ion Binding Protein Binding FK506 Binding
	Biological Process	Signal Transduction Metabolic Process Negative Regulation Of CGMP-mediated Signaling Negative Regulation Of CAMP-mediated Signaling	Protein Peptidyl-prolyl Isomerization Peptidyl-proline Modification
Pathways		cGMP effects G alpha (s) signalling events
Drugs		Caffeine Tadalafil Trapidil
Diseases
GWAS		Adiponectin levels x Mediterranean diet adherence interaction ( 33562295) Cough in response to angiotensin-converting enzyme inhibitor drugs ( 28084903) Diastolic blood pressure ( 29212154) Diffusing capacity of carbon monoxide ( 30694715) Heart rate ( 23583979) Height ( 28552196 20881960) High myopia ( 31816047) Hip circumference adjusted for BMI ( 34021172) Myopia ( 27182965) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Systolic blood pressure ( 30224653)	Alanine aminotransferase levels ( 33547301) Aspartate aminotransferase levels ( 33547301) Atrial fibrillation ( 30061737) Blood protein levels ( 30072576 29875488) Rapid functional decline in sporadic amyotrophic lateral sclerosis ( 26746183) Refractive error ( 32231278)
Interacting Genes		2 interacting genes: AGPS FKBP7	81 interacting genes: ABHD16A ADIPOQ AGPS AP1M1 APOD ASPH BMP10 BRICD5 CDIPT CERCAM CIAO2A CLCA4 CLDN19 CTSA CXCL16 DIABLO FAM3C FARS2 GET3 H4C7 HHATL HSBP1L1 IER3 IFITM3 IRF2 JOSD2 LAT MAN2B2 MIEF2 MRM1 NFU1 NPFFR2 OCIAD1 OXNAD1 PBX3 PCYT1A PDE11A PEX19 PLPP6 PPIF PRMT6 PTCD1 PTPN9 RBFA RBM45 RPRM RUSF1 SGTA SLC38A7 SLC7A14 SNX1 SNX12 STX7 STX8 SUCLA2 TARS2 TCP11X2 THAP4 THSD7B TMEM108 TMEM120B TMEM229B TMEM239 TMEM54 TMEM86A TMEM86B TMEM97 TRAM1L1 TSPAN2 TTC30A TTC30B TTPA TXNDC12 UBIAD1 UBQLN4 UPK1B VSTM4 WFDC2 WIPI2 YIPF6 ZFPL1
Entrez ID		50940	51661
HPRD ID		05391	08451
Ensembl ID		ENSG00000128655	ENSG00000079150
Uniprot IDs		Q9HCR9	Q9Y680
PDB IDs
Enriched GO Terms of Interacting Partners?
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