PAFAH1B2 and PPP1R12C

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PAFAH1B2	PPP1R12C
Description		platelet activating factor acetylhydrolase 1b catalytic subunit 2	protein phosphatase 1 regulatory subunit 12C
Image			No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Extracellular Region Nucleolus Cytoplasm Cytosol Plasma Membrane 1-alkyl-2-acetylglycerophosphocholine Esterase Complex Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen	Cytoplasm Cytoskeleton
	Molecular Function	1-alkyl-2-acetylglycerophosphocholine Esterase Activity Protein Binding Protein Homodimerization Activity Protein-containing Complex Binding Protein Heterodimerization Activity Platelet-activating Factor Acetyltransferase Activity	Enzyme Inhibitor Activity Protein Binding Phosphatase Regulator Activity Protein Kinase Binding
	Biological Process	Lipid Metabolic Process Spermatogenesis Brain Development Lipid Catabolic Process Positive Regulation Of Macroautophagy	Signal Transduction Negative Regulation Of Catalytic Activity
Pathways		Neutrophil degranulation COPI-independent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Adult body size ( 32376654) Blood protein levels ( 28240269 23696881) HDL cholesterol ( 24507774) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Protein quantitative trait loci ( 18464913) Refractive error ( 32231278) Systolic blood pressure ( 30578418)
Interacting Genes		20 interacting genes: ACIN1 ASF1A CCT3 CLVS2 CRK KMT2A PAFAH1B1 PAFAH1B3 PINX1 PPP1R12C PRKN REXO1 RPLP0 SLA SNUPN STAT3 TIMM50 TRIM55 TRIM63 ZFP36L1	27 interacting genes: ATP6V1H ATXN7 BHLHA9 C1orf109 CACNA1A CCDC185 CDC42BPA EHHADH EXOC3 FMR1 FXR1 FXR2 IL16 IMP3 MPRIP MYL2 NOD2 NXF1 PAFAH1B2 PPP1CB RBM17 SMAD3 SMARCA2 SPECC1L THOC1 TSFM USHBP1
Entrez ID		5049	54776
HPRD ID		03940	11452
Ensembl ID		ENSG00000168092	ENSG00000125503
Uniprot IDs		P68402 V9HW44	Q9BZL4
PDB IDs		1VYH
Enriched GO Terms of Interacting Partners?
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