OXT and TXNDC17

Number of citations of the paper that reports this interaction (PubMedID 14607844)
28

Data Source:
HPRD (in vitro)

		OXT	TXNDC17
Description		oxytocin/neurophysin I prepropeptide	thioredoxin domain containing 17
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Secretory Granule Terminal Bouton	Cytosol Extracellular Exosome
	Molecular Function	Neuropeptide Hormone Activity Neurohypophyseal Hormone Activity Protein Binding Oxytocin Receptor Binding	Peroxidase Activity Protein Binding Protein-disulfide Reductase (NAD(P)) Activity
	Biological Process	Response To Amphetamine Regulation Of Heart Rate Maternal Aggressive Behavior Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Heart Development Female Pregnancy Memory Grooming Behavior Response To Sucrose Positive Regulation Of Norepinephrine Secretion Response To Activity Sleep Response To Food Positive Regulation Of Prostaglandin Secretion Response To Estradiol Response To Retinoic Acid Response To Progesterone Response To Prostaglandin E Social Behavior Negative Regulation Of Urine Volume Positive Regulation Of Renal Sodium Excretion Response To Cocaine Hyperosmotic Salinity Response Maternal Behavior Sperm Ejaculation Eating Behavior Drinking Behavior Response To Peptide Hormone Response To Ether Negative Regulation Of Blood Pressure Positive Regulation Of Blood Pressure Positive Regulation Of Ossification Positive Regulation Of Female Receptivity Positive Regulation Of Synaptic Transmission Response To Glucocorticoid Response To CAMP Response To Electrical Stimulus Regulation Of Sensory Perception Of Pain Positive Regulation Of Synapse Assembly Male Mating Behavior Positive Regulation Of Penile Erection Positive Regulation Of Hindgut Contraction Negative Regulation Of Gastric Acid Secretion Positive Regulation Of Uterine Smooth Muscle Contraction Positive Regulation Of Cold-induced Thermogenesis	Tumor Necrosis Factor-mediated Signaling Pathway Cellular Oxidant Detoxification
Pathways		Vasopressin-like receptors G alpha (q) signalling events
Drugs		Oxytocin
Diseases
GWAS		Blood protein levels ( 30072576) Serum oxytocin levels ( 31361301)	LDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883)
Interacting Genes		5 interacting genes: ESR2 KMT2A OXTR PREP TXNDC17	10 interacting genes: AVP DYNLL1 EXOSC8 INCA1 INS OXT PIGS RUFY1 TINF2 TXNRD1
Entrez ID		5020	84817
HPRD ID		08880	11656
Ensembl ID		ENSG00000101405	ENSG00000129235
Uniprot IDs		P01178 X5D7M6	A0A140VJY7 Q9BRA2
PDB IDs			1WOU
Enriched GO Terms of Interacting Partners?
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