OVGP1 and DPYD

		OVGP1	DPYD
Description		oviductal glycoprotein 1	dihydropyrimidine dehydrogenase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytosol Microtubule Cytoskeleton Transport Vesicle Egg Coat Intracellular Membrane-bounded Organelle Perivitelline Space	Cytoplasm Cytosol
	Molecular Function	Chitinase Activity Chitin Binding	Uracil Binding Protein Binding Dihydropyrimidine Dehydrogenase (NADP+) Activity Protein Homodimerization Activity Metal Ion Binding Flavin Adenine Dinucleotide Binding NADP Binding Iron-sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	Carbohydrate Metabolic Process Chitin Catabolic Process Single Fertilization Female Pregnancy Negative Regulation Of Binding Of Sperm To Zona Pellucida	Purine Nucleobase Catabolic Process Pyrimidine Nucleobase Catabolic Process Thymine Catabolic Process Uracil Catabolic Process Thymidine Catabolic Process CMP Catabolic Process DCMP Catabolic Process Beta-alanine Biosynthetic Process UMP Catabolic Process DUMP Catabolic Process
Pathways		Interaction With Cumulus Cells And The Zona Pellucida	Pyrimidine catabolism
Drugs			(5S)-5-Iododihydro-2,4(1H,3H)-pyrimidinedione NADPH 6-Carboxymethyluracil Flavin adenine dinucleotide Flavin mononucleotide Uracil Eniluracil 5-Iodouracil Gimeracil Tegafur-uracil
Diseases
GWAS		Response to antidepressants (symptom improvement) ( 29160301)	Adult body size ( 32376654) Adverse response to drug ( 30420678) Anthropometric traits (multi-trait analysis) ( 30166351) Anxiety/tension (special factor of neuroticism) ( 30867560) Autism spectrum disorder or schizophrenia ( 28540026) Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Body mass index ( 25673413 29273807) Borderline personality disorder ( 28632202) Chronotype ( 30696823) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Coronary artery disease ( 29212778) Daytime nap ( 33568662) Extremely high intelligence ( 29520040) Face memory ( 31596458) Feeling nervous ( 29500382) Gastroesophageal reflux disease ( 31527586) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Heel bone mineral density ( 30598549) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Irritable mood ( 29500382) Menarche (age at onset) ( 25231870) Metabolite levels ( 23823483) Methadone dose in opioid dependence ( 28115739) Platelet count ( 21507922) Regular attendance at a pub or social club ( 29970889) Schizophrenia ( 25056061 29483656 22688191 30285260 23974872) Serum metabolite levels ( 33031748) Sleep duration ( 30531941) Sleep duration (short sleep) ( 30846698) Triglyceride levels ( 32203549 32154731) Waist-to-hip ratio adjusted for BMI ( 28552196)
Interacting Genes		5 interacting genes: ASL DPYD MYH9 RASA4 STATH	11 interacting genes: CLK1 CPB2 CSDE1 GOPC HPCA KCNJ4 LXN OVGP1 RPS6KA3 SRC SULT2A1
Entrez ID		5016	1806
HPRD ID		04658	02036
Ensembl ID		ENSG00000085465	ENSG00000188641
Uniprot IDs		Q12889 Q86YN0	Q12882
PDB IDs
Enriched GO Terms of Interacting Partners?
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