OTC and TOMM20

Number of citations of the paper that reports this interaction (PubMedID 9756929)
12

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		OTC	TOMM20
Description		ornithine transcarbamylase	translocase of outer mitochondrial membrane 20
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Intracellular Membrane-bounded Organelle	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Outer Membrane Translocase Complex Integral Component Of Mitochondrial Outer Membrane Mitochondria-associated Endoplasmic Reticulum Membrane
	Molecular Function	Ornithine Carbamoyltransferase Activity Phospholipid Binding Amino Acid Binding Phosphate Ion Binding Identical Protein Binding	Protein Binding Protein Transmembrane Transporter Activity Protein-transporting ATPase Activity Mitochondrion Targeting Sequence Binding Unfolded Protein Binding
	Biological Process	Urea Cycle Liver Development Ornithine Catabolic Process Midgut Development Response To Xenobiotic Stimulus Response To Zinc Ion Citrulline Biosynthetic Process Response To Insulin Arginine Biosynthetic Process Via Ornithine Anion Homeostasis Response To Biotin Ammonium Homeostasis	Protein Targeting To Mitochondrion Response To Muscle Activity TRNA Import Into Mitochondrion Protein Import Into Mitochondrial Matrix Response To 3,3',5-triiodo-L-thyronine
Pathways		Mitochondrial protein import Mitochondrial protein import Urea cycle	Mitochondrial protein import PINK1-PRKN Mediated Mitophagy Ub-specific processing proteases
Drugs		Ornithine Citrulline N-(Phosphonoacetyl)-L-Ornithine Norvaline
Diseases
GWAS			Apolipoprotein A1 levels ( 32203549) Cholesterol, total ( 20686565) Cobalt levels ( 26025379) Immune reponse to smallpox (secreted IL-2) ( 22610502) LDL cholesterol ( 20686565) LDL cholesterol levels ( 32203549) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		1 interacting genes: TOMM20	19 interacting genes: AIP APOA1 ATXN1 BAG6 BCL2 CDC73 CEP126 DHFR FBXO7 FEZ1 HAP1 HSD17B10 OTC PPHLN1 PTN SNCA TOMM22 UCP1 VDAC1
Entrez ID		5009	9804
HPRD ID		08947	03507
Ensembl ID		ENSG00000036473	ENSG00000173726
Uniprot IDs		P00480	A0A024R3W2 Q15388
PDB IDs		1C9Y 1EP9 1FVO 1OTH	4APO
Enriched GO Terms of Interacting Partners?
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