OPRK1 and NKG7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		OPRK1	NKG7
Description		opioid receptor kappa 1	natural killer cell granule protein 7
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Integral Component Of Synaptic Vesicle Membrane Dendrite Neuron Projection Perikaryon Axon Terminus Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Membrane	Lysosome Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	G Protein-coupled Receptor Activity G Protein-coupled Opioid Receptor Activity Protein Binding Receptor Serine/threonine Kinase Binding Dynorphin Receptor Activity Peptide Binding Neuropeptide Binding	Protein Binding
	Biological Process	Immune Response Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Chemical Synaptic Transmission Sensory Perception Locomotory Behavior Response To Radiation Sensory Perception Of Pain Adenylate Cyclase-inhibiting Opioid Receptor Signaling Pathway Response To Insulin Positive Regulation Of Dopamine Secretion Negative Regulation Of Luteinizing Hormone Secretion G Protein-coupled Opioid Receptor Signaling Pathway Positive Regulation Of Locomotion Maternal Behavior Eating Behavior Response To Morphine Response To Estrogen Estrous Cycle Response To Ethanol Regulation Of Saliva Secretion Behavioral Response To Cocaine Sensory Perception Of Temperature Stimulus Defense Response To Virus Regulation Of Sensory Perception Of Pain Cellular Response To Lipopolysaccharide Cellular Response To Glucose Stimulus Positive Regulation Of P38MAPK Cascade Positive Regulation Of Potassium Ion Transmembrane Transport Response To Acrylamide Positive Regulation Of Eating Behavior Conditioned Place Preference
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events MECP2 regulates neuronal receptors and channels
Drugs		Tramadol Atomoxetine Morphine Codeine Amitriptyline Hydromorphone Mirtazapine Progesterone Meperidine Oxycodone Dextromethorphan Lamotrigine Butorphanol Dextropropoxyphene Pentazocine Naltrexone Sufentanil Fentanyl Levomenthol Loperamide Nalbuphine Levorphanol Remifentanil Buprenorphine Naloxone Dezocine Ketamine Aripiprazole 3-Methylthiofentanyl Diamorphine Etorphine Carfentanil Diprenorphine Dihydromorphine 3-Methylfentanyl V1003 Asimadoline CR665 ADL 10-0101 Mianserin Tapentadol Nalmefene Alvimopan Morphine glucuronide Ketobemidone Methylnaltrexone Butyrfentanyl Pholcodine Eluxadoline Opium Pentoxyverine Naldemedine Loxicodegol
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Body size at age 10 ( 32376654) IgE levels in asthmatics (D.p. specific) ( 23967269) Modic changes ( 30808802) Systolic blood pressure x quantitative lifestyle risk score interaction (2df test) ( 32227373)	Neutrophil count ( 32888494 27863252) Neutrophil percentage of white cells ( 32888494)
Interacting Genes		6 interacting genes: GABARAPL1 GNA15 GPRASP1 NKG7 OPRD1 SLC9A3R1	47 interacting genes: AGTRAP AMIGO1 AQP6 ARL13B ATP6AP2 BAMBI CD53 CD79A CLDN7 CLEC2D CLEC4E CLSTN3 CREB3 EBP EDA2R ERGIC3 FAM210B FFAR2 FNDC9 GJA5 GORAB GPX8 ISLR2 KLRC1 LHFPL5 LMNA MFSD6 MGST3 MS4A3 MSR1 MUC1 OPRK1 PEX12 PLEKHF2 PRRG2 RAMP1 RNF24 SLC18A2 SLC30A8 STOM STX1A TLCD4 TMEM106C TMEM130 TMEM139 TMEM80 TMEM88
Entrez ID		4986	4818
HPRD ID		01309	16188
Ensembl ID		ENSG00000082556	ENSG00000105374
Uniprot IDs		A0A5F9ZI09 P41145	Q16617
PDB IDs		2A0D 2IQN 4DJH 6B73 6VI4
Enriched GO Terms of Interacting Partners?
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