ATP5F1A and HSD17B10

Number of citations of the paper that reports this interaction (PubMedID 22496890)
6

Data Source:
BioGRID (two hybrid)

		ATP5F1A	HSD17B10
Description		ATP synthase F1 subunit alpha	hydroxysteroid 17-beta dehydrogenase 10
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Proton-transporting ATP Synthase Complex Mitochondrial Proton-transporting ATP Synthase, Catalytic Core Mitochondrial Matrix Plasma Membrane Membrane Proton-transporting ATP Synthase Complex Proton-transporting ATP Synthase Complex, Catalytic Core F(1) Extracellular Exosome	Cytoplasm Mitochondrion Mitochondrial Matrix Plasma Membrane Mitochondrial Ribonuclease P Complex Mitochondrial Nucleoid
	Molecular Function	RNA Binding Protein Binding ATP Binding MHC Class I Protein Binding ADP Binding Angiostatin Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism	TRNA Binding RNA Binding 3-hydroxyacyl-CoA Dehydrogenase Activity Estradiol 17-beta-dehydrogenase Activity Protein Binding Cholate 7-alpha-dehydrogenase Activity Testosterone Dehydrogenase [NAD(P)] Activity 17-beta-hydroxysteroid Dehydrogenase (NAD+) Activity 3-hydroxy-2-methylbutyryl-CoA Dehydrogenase Activity Testosterone Dehydrogenase (NAD+) Activity Androstan-3-alpha,17-beta-diol Dehydrogenase Activity Chenodeoxycholate 7-alpha-dehydrogenase (NAD+) Activity Isoursodeoxycholate 7-beta-dehydrogenase (NAD+) Activity Ursodeoxycholate 7-beta-dehydrogenase (NAD+) Activity
	Biological Process	Negative Regulation Of Endothelial Cell Proliferation Lipid Metabolic Process ATP Biosynthetic Process ATP Synthesis Coupled Proton Transport Mitochondrial ATP Synthesis Coupled Proton Transport Positive Regulation Of Blood Vessel Endothelial Cell Migration	Isoleucine Catabolic Process Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Beta-oxidation Bile Acid Biosynthetic Process Mitochondrion Organization C21-steroid Hormone Metabolic Process Androgen Metabolic Process Estrogen Metabolic Process Protein Homotetramerization Brexanolone Metabolic Process Mitochondrial TRNA Methylation Mitochondrial TRNA 5'-end Processing Mitochondrial TRNA 3'-end Processing
Pathways		Mitochondrial protein import Formation of ATP by chemiosmotic coupling Cristae formation	tRNA processing in the mitochondrion tRNA modification in the mitochondrion Branched-chain amino acid catabolism rRNA processing in the mitochondrion
Drugs		Quercetin 1-ACETYL-2-CARBOXYPIPERIDINE AUROVERTIN B Piceatannol N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE Artenimol	NADH 1-Azepan-1-Yl-2-Phenyl-2-(4-Thioxo-1,4-Dihydro-Pyrazolo[3,4-D]Pyrimidin-5-Yl)Ethanone Adduct Omega-3-carboxylic acids
Diseases
GWAS			Bipolar disorder ( 31043756) Body mass index ( 28892062)
Interacting Genes		20 interacting genes: ABCC1 AIMP1 APP ATP5F1C ATPAF2 CSNK2A1 HSD17B10 HSPB2 LINC01554 NPSR1 OGT PTEN PTPRF SCGN SHBG SMARCB1 YWHAB YWHAG YWHAQ YWHAZ	32 interacting genes: ALDH3B1 ALDOA APP ATP5F1A CDC42 CHD3 CPS1 CS ETFDH FAF1 GLUD1 GLUL HADHA HADHB HMGCL HMGCS2 HTRA2 KDM6A MDH1 OGDH PDHB PDHX PRKN PTEN PYGL TOMM20 TOMM22 TOMM40 TRAF3IP2 TRAF5 TRAF6 UBE2D1
Entrez ID		498	3028
HPRD ID		01258	02223
Ensembl ID		ENSG00000152234	ENSG00000072506
Uniprot IDs		P25705 V9HW26	A0A0S2Z410 Q99714
PDB IDs			1F67 1SO8 1U7T 2O23
Enriched GO Terms of Interacting Partners?
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