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NVL and RPL5
Number of citations of the paper that reports this interaction (PubMedID
15469983
)
16
Data Source:
HPRD
(in vivo, in vitro, two hybrid)
NVL
RPL5
Description
nuclear VCP like
ribosomal protein L5
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Telomerase Holoenzyme Complex
Nucleolus
Membrane
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Endoplasmic Reticulum
Cytosol
Focal Adhesion
Membrane
Cytosolic Large Ribosomal Subunit
Cytosolic Ribosome
Protein-containing Complex
Synapse
Extracellular Exosome
Ribonucleoprotein Complex
Molecular Function
RNA Binding
Protein Binding
ATP Binding
ATP Hydrolysis Activity
Preribosome Binding
RNA Binding
MRNA 3'-UTR Binding
Structural Constituent Of Ribosome
Protein Binding
5S RRNA Binding
Ubiquitin Protein Ligase Binding
MRNA 5'-UTR Binding
Ubiquitin Ligase Inhibitor Activity
Biological Process
RRNA Processing
Positive Regulation Of Protein Binding
Ribosome Biogenesis
Ribosomal Large Subunit Biogenesis
Positive Regulation Of Telomerase Activity
Regulation Of Protein Localization To Nucleolus
Ribosomal Large Subunit Assembly
Cytoplasmic Translation
RRNA Processing
Translation
Positive Regulation Of Gene Expression
Ribosomal Large Subunit Biogenesis
Positive Regulation Of Translation
Protein Stabilization
Regulation Of Signal Transduction By P53 Class Mediator
Negative Regulation Of Ubiquitin Protein Ligase Activity
Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Protein Neddylation
Pathways
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Formation of a pool of free 40S subunits
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Response of EIF2AK4 (GCN2) to amino acid deficiency
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
HDL cholesterol levels in HIV infection (
33109212
)
Major depressive disorder (
21042317
)
Mean corpuscular hemoglobin (
32888494
)
Allergic disease (asthma, hay fever or eczema) (
29785011
)
Height (
20881960
)
Mean corpuscular hemoglobin (
32888494
)
Mean reticulocyte volume (
32888494
)
Multiple sclerosis (
19525955
17660530
)
Interacting Genes
10 interacting genes:
CRMP1
FBXO7
HSPB1
LINC00839
NDUFAF1
OSGEP
RNF4
RPL5
TTF2
UBE2I
26 interacting genes:
CLK1
CSNK2A1
CSNK2B
DCC
EIF5A
ERCC6
HARS1
IPO13
IPO5
IPO7
KPNB1
MAP3K14
MDM2
NVL
OGT
PDCD4
PPM1D
RNA5S7
SPIN1
SPP1
TNIP1
TNPO1
TP73
TSC22D1
UPF2
VHL
Entrez ID
4931
6125
HPRD ID
03887
04699
Ensembl ID
ENSG00000143748
ENSG00000122406
Uniprot IDs
B4DF43
O15381
A2RUM7
P46777
PDB IDs
2X8A
6RO1
4UG0
4V6X
5AJ0
5LKS
5T2C
6EK0
6IP5
6IP6
6IP8
6LQM
6LSR
6LSS
6LU8
6OLE
6OLF
6OLG
6OLI
6OLZ
6OM0
6OM7
6QZP
6W6L
6XA1
6Y0G
6Y2L
6Y57
6Y6X
6Z6L
6Z6M
6Z6N
6ZM7
6ZME
6ZMI
6ZMO
7BHP
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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