NUP98 and CBFA2T3

		NUP98	CBFA2T3
Description		nucleoporin 98 and 96 precursor	CBFA2/RUNX1 partner transcriptional co-repressor 3
Image			No pdb structure
GO Annotations	Cellular Component	Kinetochore Nuclear Envelope Nuclear Pore Nucleoplasm Cytosol Nuclear Body Nuclear Pore Outer Ring Nuclear Membrane Nuclear Periphery Nuclear Inclusion Body Intracellular Membrane-bounded Organelle Nuclear Pore Nuclear Basket Ribonucleoprotein Complex	Golgi Membrane Nucleus Nucleoplasm Nucleolus
	Molecular Function	Transcription Coactivator Activity MRNA Binding Transporter Activity Protein Binding Nuclear Localization Sequence Binding Serine-type Peptidase Activity Structural Constituent Of Nuclear Pore Promoter-specific Chromatin Binding	Transcription Corepressor Activity Protein Binding Metal Ion Binding
	Biological Process	Proteolysis Protein Import Into Nucleus Nucleocytoplasmic Transport Nuclear Pore Organization Positive Regulation Of Transcription, DNA-templated Positive Regulation Of MRNA Splicing, Via Spliceosome MRNA Transport Nuclear Pore Complex Assembly	Response To Hypoxia Transcription, DNA-templated Negative Regulation Of Cell Population Proliferation Granulocyte Differentiation Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Glycolytic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Aerobic Respiration
Pathways
Drugs
Diseases
GWAS		Malaria ( 31844061) Metabolite levels (Dihydroxy docosatrienoic acid) ( 23934736)	Annualised percent change of cerebrospinal fluid AB1-42 levels ( 31370031) Carotid intima media thickness ( 30510157) Carotid intima media thickness (mean) ( 31801372) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Hair color ( 26926045) Hemoglobin levels ( 32327693) Immature fraction of reticulocytes ( 32888494) Levodopa-induced dyskinesia in levodopa treated Parkinson's disease ( 32733355) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494) Mean platelet volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Multiple sclerosis ( 31604244) Neutrophil count ( 32888494) Red cell distribution width ( 32888494) Red vs. brown/black hair color ( 30531825) Social autistic-like traits ( 24133439) Vitiligo ( 27723757)
Interacting Genes		30 interacting genes: APC CBFA2T3 CHMP5 CREBBP CSNK2A1 CYFIP1 EP300 HBE1 HDAC1 IPO5 KCNQ1 KPNB1 MUC2 NFX1 NUP133 NUP214 NUP62 NUP88 NXF1 PSMD13 RAE1 RCC1 RNH1 RRM1 SEC13 SLC22A18AS TNPO1 TNPO2 TPR UTRN	24 interacting genes: ARHGEF6 CBFA2T2 CHRM4 EPM2AIP1 GAS8 GATAD2A GMEB2 HDAC1 HDAC3 MATN2 NUP98 PIN1 PRKAR2A RTN4IP1 RUNX1 RUNX1T1 SEC24A TCF3 VPS37C ZBTB33 ZBTB38 ZBTB4 ZBTB47 ZNF652
Entrez ID		4928	863
HPRD ID		03012	04847
Ensembl ID		ENSG00000110713	ENSG00000129993
Uniprot IDs		P52948	O75081
PDB IDs		1KO6 2Q5X 2Q5Y 3MMY 4OWR 5A9Q 6BZM
Enriched GO Terms of Interacting Partners?
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