NUCB1 and NDN

Number of citations of the paper that reports this interaction (PubMedID 10915798)
27

Data Source:
HPRD (two hybrid)

		NUCB1	NDN
Description		nucleobindin 1	necdin, MAGE family member
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Early Endosome Endoplasmic Reticulum Lumen Rough Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi-associated Vesicle Cis-Golgi Network Trans-Golgi Network Membrane Golgi Cisterna Membrane Extracellular Exosome Extrinsic Component Of Golgi Membrane Lumenal Side Of Golgi Membrane	Nucleus Nucleoplasm Centrosome Cytosol Protein-containing Complex Cell Projection Perikaryon
	Molecular Function	G-protein Alpha-subunit Binding DNA Binding Guanyl-nucleotide Exchange Factor Activity Calcium Ion Binding Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Gamma-tubulin Binding Promoter-specific Chromatin Binding
	Biological Process	Small GTPase Mediated Signal Transduction Regulation Of Catalytic Activity Response To Cisplatin Regulation Of Protein Targeting	Negative Regulation Of Transcription By RNA Polymerase II Neuron Migration Respiratory System Process Axonal Fasciculation Central Nervous System Development Negative Regulation Of Cell Population Proliferation Glial Cell Migration Post-embryonic Development Sensory Perception Of Pain Regulation Of Growth Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Transcription By RNA Polymerase II Neurotrophin TRK Receptor Signaling Pathway Axon Extension Multicellular Organismal Homeostasis Genetic Imprinting Positive Regulation Of Protein Deacetylation
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	Interleukin-4 and Interleukin-13 signaling
Drugs		Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS			Body size at age 10 ( 32376654) Depressive symptoms (SSRI exposure interaction) ( 25649181) HDL cholesterol levels ( 32203549) Parkinson's disease (age of onset) ( 33884653) Plasma anti-thyroid peroxidase levels ( 29678681) Serum metabolite concentrations in chronic kidney disease ( 29545352)
Interacting Genes		18 interacting genes: GNAI1 GNAI2 GNAI3 GNAO1 GNAS GNAZ HIVEP1 HOXA1 MYC NDN PLOD2 PTGS1 PTGS2 RBL1 REL SET SIRPA XPO1	47 interacting genes: APBB1IP ARSL BLOC1S6 CALCOCO2 CCDC136 CDR2 DTNBP1 E2F1 E2F4 EEF1AKMT1 EGFR EID1 EPAS1 FAM131C FSD2 FXR2 GKAP1 GOLGA2 HIF1A HNRNPU IFFO1 IL1A IL32 IRS4 LAX1 LPXN MIER2 MKRN2 MYG1 NEFL NGFR NUBP1 NUCB1 NUCB2 P4HA3 PALS2 PJA1 PPARGC1A PPFIA1 SERTAD3 SIRT1 SSX2IP TFIP11 TP53 U2AF1 ZBTB1 ZBTB7B
Entrez ID		4924	4692
HPRD ID		03205	03667
Ensembl ID		ENSG00000104805	ENSG00000182636
Uniprot IDs		A8K7Q1 Q02818	Q99608 X5D982
PDB IDs		1SNL
Enriched GO Terms of Interacting Partners?
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