NOP2 and CDCA7L

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		NOP2	CDCA7L
Description		NOP2 nucleolar protein	cell division cycle associated 7 like
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus	Fibrillar Center Nucleus Nucleoplasm Nucleolus Cytosol
	Molecular Function	RNA Binding Protein Binding RRNA (cytosine-C5-)-methyltransferase Activity	Protein Binding
	Biological Process	Ribosomal Large Subunit Assembly Maturation Of LSU-rRNA RNA Methylation Positive Regulation Of Cell Population Proliferation RRNA Base Methylation Regulation Of Signal Transduction By P53 Class Mediator	Regulation Of Transcription, DNA-templated Positive Regulation Of Cell Population Proliferation
Pathways		rRNA modification in the nucleus and cytosol TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation
Drugs
Diseases
GWAS			Breast cancer ( 29059683) Gamma glutamyl transferase levels ( 33339817) Height ( 20189936) Multiple myeloma ( 26007630) Multiple myeloma and monoclonal gammopathy ( 26007630) Pre-treatment viral load in HIV-1 infection ( 31219150) Squamous cell lung carcinoma ( 28604730) Urate levels in obese individuals ( 25811787)
Interacting Genes		11 interacting genes: CDC42 CDCA7L CEP70 KPNA6 MCRS1 MT1F NPM1 PTPRJ SUMO2 UBE2I VPS52	68 interacting genes: ABT1 ANKRD1 ANKRD11 ANKRD23 AVPI1 AXIN1 BAG5 BEND7 BHLHB9 BRPF1 BYSL CARD9 CAVIN1 CCDC116 CCDC33 CEP70 CTNNBL1 DAXX DEDD2 DMAP1 EIF4A3 FAM217B FAM9B GOLGA2 HSF2BP ING5 JADE2 KRTAP10-7 LMO1 MCRS1 MDFI MEOX2 MFAP1 MLH1 MORN3 MRPL28 MYC NDUFB7 NOL12 NOP2 PBX1 PBX2 PICK1 PIH1D1 PIP4K2B PPP1R16A PPP1R16B PRDM14 PRPF31 RRP7A SNRNP48 SSX1 SSX2IP STX11 SUV39H1 TADA2A TFPT TNNI1 TRAF3IP3 TRIM42 UBL4A UTP3 VDR ZGPAT ZNF250 ZNF438 ZNF620 ZNF821
Entrez ID		4839	55536
HPRD ID		01244	11481
Ensembl ID		ENSG00000111641	ENSG00000164649
Uniprot IDs		P46087	A0A024RA51 A8K8X5 Q96GN5
PDB IDs			5YI9 6EMO
Enriched GO Terms of Interacting Partners?
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