ATP1B1 and CD84

		ATP1B1	CD84
Description		ATPase Na+/K+ transporting subunit beta 1	CD84 molecule
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Sodium:potassium-exchanging ATPase Complex Caveola Intercalated Disc Membrane Basolateral Plasma Membrane Apical Plasma Membrane Lateral Plasma Membrane T-tubule Organelle Membrane Sperm Flagellum Sarcolemma Extracellular Exosome Extracellular Vesicle	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	ATPase Activator Activity P-type Sodium:potassium-exchanging Transporter Activity Protein Binding Protein C-terminus Binding Protein Kinase Binding MHC Class II Protein Complex Binding Protein-macromolecule Adaptor Activity Protein Heterodimerization Activity ATPase Binding	Protein Binding Identical Protein Binding
	Biological Process	Response To Hypoxia Cellular Calcium Ion Homeostasis Cellular Sodium Ion Homeostasis Cell Adhesion Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Regulation Of Gene Expression Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Cellular Potassium Ion Homeostasis Positive Regulation Of ATPase Activity Sodium Ion Transmembrane Transport Sodium Ion Export Across Plasma Membrane Protein Transport Into Plasma Membrane Raft ATP Metabolic Process Regulation Of Catalytic Activity Protein Stabilization Relaxation Of Cardiac Muscle Cardiac Muscle Contraction Protein Localization To Plasma Membrane Membrane Repolarization Membrane Repolarization During Cardiac Muscle Cell Action Potential Cell Communication By Electrical Coupling Involved In Cardiac Conduction Cation Transmembrane Transport Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Sodium Ion Export Across Plasma Membrane Positive Regulation Of Calcium:sodium Antiporter Activity Positive Regulation Of Potassium Ion Import Across Plasma Membrane Positive Regulation Of P-type Sodium:potassium-exchanging Transporter Activity Potassium Ion Import Across Plasma Membrane	Adaptive Immune Response Autophagy Defense Response Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Negative Regulation Of Granulocyte Macrophage Colony-stimulating Factor Production Negative Regulation Of Interleukin-18 Production Negative Regulation Of Interleukin-6 Production Positive Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Mast Cell Activation T Cell Activation Regulation Of Macrophage Activation Negative Regulation Of Mast Cell Degranulation Innate Immune Response Positive Regulation Of Monocyte Chemotactic Protein-1 Production Regulation Of Store-operated Calcium Entry
Pathways		Basigin interactions Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS	Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778 33020668) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits ( 25055868) Electrocardiographic traits (multivariate) ( 32602732) Fuchs's corneal dystrophy ( 28358029) Haemorrhoidal disease ( 33888516) Keratoconus ( 33649486) Mitochondrial DNA levels ( 25240745) QT interval ( 23166209 29213071 24952745 19305409 29874175) Rosacea symptom severity ( 29771307)	Response to anti-TNF therapy in rheumatoid arthritis ( 23555300)
Interacting Genes		29 interacting genes: AGTR1 BACE1 BARD1 BRCA1 CD84 CREG1 CRIP2 DDAH2 EGFR EZH2 FXYD1 FXYD7 GCH1 HCRTR1 HTR2B KMT2B LRIF1 NDRG2 OGT PAXIP1 PRRX1 PSME1 SERPINC1 THOC1 TM4SF1 TRIM14 TRMT2A TSC22D2 USP4	3 interacting genes: ATP1B1 SH2D1A SH2D1B
Entrez ID		481	8832
HPRD ID		01663	05151
Ensembl ID		ENSG00000143153	ENSG00000066294
Uniprot IDs		A3KLL5 P05026	Q9UIB8
PDB IDs			2PKD
Enriched GO Terms of Interacting Partners?
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