NFIX and NRTN

		NFIX	NRTN
Description		nuclear factor I X	neurturin
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Extracellular Region Axon
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	Signaling Receptor Binding Growth Factor Activity Glial Cell-derived Neurotrophic Factor Receptor Binding Receptor Tyrosine Kinase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Replication Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	MAPK Cascade Neural Crest Cell Migration Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Nervous System Development Nerve Development Neuron Projection Development
Pathways		RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation	NCAM1 interactions RAF/MAP kinase cascade RET signaling
Drugs
Diseases
GWAS		Bipolar disorder ( 28115744) Body mass index ( 25673413) Brain morphology (MOSTest) ( 32665545) Clozapine-induced agranulocytosis ( 25187353) Cortical surface area ( 32963231) Cortical volume ( 32963231) Granulocyte percentage of myeloid white cells ( 27863252) Heel bone mineral density ( 30598549) Hemoglobin ( 32888494) Hip index ( 34021172) Intelligence (MTAG) ( 29326435) Lymphocyte counts ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Monocyte count ( 32888494 27863252) Monocyte percentage of white cells ( 32888494 27863252) Plateletcrit ( 32888494) Refractive error ( 32231278)	Advanced age-related macular degeneration ( 26691988) Blood protein levels ( 29875488) Chronotype ( 30696823) N-glycan levels ( 21908519 21203500 31163085)
Interacting Genes		16 interacting genes: ARL4A GADD45B GZMA JMJD6 MATK MLH1 MLLT1 NFIB NRTN PIR POLR2E QRICH1 RFX1 RWDD1 SKI ZNF614	4 interacting genes: GFRA1 GFRA2 NFIX RET
Entrez ID		4784	4902
HPRD ID		01234	03604
Ensembl ID		ENSG00000008441	ENSG00000171119
Uniprot IDs		B4DHW2 Q14938	Q99748
PDB IDs			5MR4 5MR5 5MR9 5NMZ 6GL7 6Q2O 6Q2R
Enriched GO Terms of Interacting Partners?
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