NFIC and ZCCHC14

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1103

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NFIC	ZCCHC14
Description		nuclear factor I C	zinc finger CCHC-type containing 14
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Fibrillar Center Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Sequence-specific Double-stranded DNA Binding	Nucleic Acid Binding Protein Binding Zinc Ion Binding Phosphatidylinositol Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Replication Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways		RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation
Drugs
Diseases
GWAS		Alzheimer's disease (APOE e4 interaction) ( 28183528) Apolipoprotein A1 levels ( 32203549) Automobile speeding propensity ( 30643258) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) Heel bone mineral density ( 30598549) Height ( 28552196 20881960 25282103 31562340) High light scatter reticulocyte count ( 32888494) Hip circumference ( 28552196) Hip circumference adjusted for BMI ( 28552196) Monocyte count ( 32888494) Nevus count or cutaneous melanoma ( 30429480) Platelet count ( 32888494) Plateletcrit ( 32888494) Serum urate levels in chronic kidney disease ( 30181573) Weight ( 28552196) Youthful appearance (self-reported) ( 32339537)	Anxiety ( 33859377) Broad depression or schizophrenia ( 30626913) Hippocampal volume in mild cognitive impairment ( 29274321) Ischemic stroke ( 29531354) Ischemic stroke (small-vessel) ( 29531354) Lacunar stroke ( 33773637) Major depressive disorder ( 22472876) Migraine ( 27182965 27322543) Neuroticism ( 29255261) Refractive error ( 32231278) Small vessel stroke ( 27997041) Stroke ( 29531354)
Interacting Genes		26 interacting genes: CBLC CREBBP DACH1 EPHA2 ERGIC1 FBXO7 GLIS1 GLIS2 GLRX LATS2 LLPH MAP2K3 MAPK14 MYC NFIB NSD3 RELA RFX1 SOX3 TEAD2 TH TKTL2 TLX1 TPD52L3 ZCCHC14 ZKSCAN7	16 interacting genes: CYSRT1 FHL3 MYO15B MYOG NFIC PLEKHG4 PRR20A PRR20B PRR20C PRR20D PRR20E SMAD3 TENT4B TET2 TNS2 USP54
Entrez ID		4782	23174
HPRD ID		09009	18316
Ensembl ID		ENSG00000141905	ENSG00000140948
Uniprot IDs		B7Z4T6 P08651	Q8WYQ9
PDB IDs
Enriched GO Terms of Interacting Partners?
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