NASP and ULK2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NASP	ULK2
Description		nuclear autoantigenic sperm protein	unc-51 like autophagy activating kinase 2
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Protein-containing Complex	Cytoplasm Cytoplasmic Vesicle Membrane Phagophore Assembly Site Membrane
	Molecular Function	Protein Binding Histone Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Blastocyst Development DNA Replication DNA Replication-dependent Nucleosome Assembly DNA Replication-independent Nucleosome Assembly Male Gonad Development Protein Transport Response To Testosterone CENP-A Containing Nucleosome Assembly Histone Exchange	Autophagosome Assembly Autophagy Of Mitochondrion Autophagy Signal Transduction Peptidyl-serine Phosphorylation Piecemeal Microautophagy Of The Nucleus Response To Starvation Late Nucleophagy Protein Autophosphorylation Negative Regulation Of Collateral Sprouting Axon Extension Reticulophagy Positive Regulation By Symbiont Of Host Autophagy
Pathways
Drugs			Fostamatinib
Diseases
GWAS		Blood metabolite levels ( 24816252) Blood protein levels ( 28240269) Body mass index ( 26426971) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Hematocrit ( 27863252) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		27 interacting genes: CDC42 FXR2 H1-1 H1-2 H3-4 H3-5 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 HDAC6 LUC7L2 MTNR1A OGT PTK2 ST3GAL3 TERF2 TERF2IP ULK2	16 interacting genes: ATG14 DIXDC1 DUXAP9 EEF1B2 GABARAP GABARAPL2 LNX1 LUC7L2 NASP POLA2 RAI1 SETDB1 SQSTM1 SYNGAP1 TNPO1 ZNF32
Entrez ID		4678	9706
HPRD ID		04423	10556
Ensembl ID		ENSG00000132780	ENSG00000083290
Uniprot IDs		P49321 Q5T626	Q8IYT8
PDB IDs			6QAT 6QAU 6QAV 6YID
Enriched GO Terms of Interacting Partners?
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