MYH3 and DYSF

Number of citations of the paper that reports this interaction (PubMedID 23414517)
13

Data Source:
BioGRID (two hybrid)

		MYH3	DYSF
Description		myosin heavy chain 3	dysferlin
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Muscle Myosin Complex Sarcomere Myosin Filament Extracellular Exosome	Endosome Early Endosome Late Endosome Plasma Membrane Integral Component Of Membrane Endocytic Vesicle T-tubule Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Centriolar Satellite Sarcolemma Extracellular Exosome
	Molecular Function	Microfilament Motor Activity Calmodulin Binding ATP Binding ATP Hydrolysis Activity Myosin Phosphatase Activity Actin Filament Binding	Calcium Ion Binding Protein Binding Phospholipid Binding Calcium-dependent Phospholipid Binding
	Biological Process	Skeletal Muscle Contraction Protein Dephosphorylation Muscle Organ Development Actin Filament-based Movement Muscle Filament Sliding Embryonic Limb Morphogenesis Sarcomere Organization ATP Metabolic Process Face Morphogenesis	Plasma Membrane Repair Monocyte Activation Involved In Immune Response Macrophage Activation Involved In Immune Response Vesicle Fusion Plasma Membrane Organization T-tubule Organization Negative Regulation Of Phagocytosis Membrane Fusion
Pathways		Striated Muscle Contraction	Smooth Muscle Contraction Smooth Muscle Contraction
Drugs
Diseases
GWAS		Post bronchodilator percent predicted FEV1 in smoking ( 30068317) Relative hand skill in reading disability ( 24068947)	Asthma ( 32296059) Extremely high intelligence ( 29520040) General cognitive ability ( 29844566) Hip circumference adjusted for BMI ( 28552196 34021172) Nonalcoholic steatohepatitis-derived hepatocellular carcinoma ( 29385134) PR interval in Tripanosoma cruzi seropositivity ( 24324551) Protein quantitative trait loci ( 18464913) Urate levels in overweight individuals ( 25811787)
Interacting Genes		11 interacting genes: APPL1 CLIP4 DYSF GNG5 LAIR1 LAMTOR5 OPTN PPP1R7 PRKD3 SNAPIN TULP3	40 interacting genes: AKAP1 ANKRD1 ANXA1 ANXA2 APPL1 CAPN3 CAV3 CMYA5 COL12A1 COL6A3 DGKD DHX15 DNAJB6 EEF1A1 EEF1G FAM120A GNL3 KARS1 KIF1B MORF4L1 MYBPC1 MYBPC2 MYH3 MYOM1 MYOM2 NPHP3 OPTN OS9 PHF1 PLP1 RNF10 RNF2 SAMHD1 SGCG SLC12A6 SNAPIN TAF1 XIRP2 XRCC6 ZNF23
Entrez ID		4621	8291
HPRD ID		01172	04307
Ensembl ID		ENSG00000109063	ENSG00000135636
Uniprot IDs		P11055 Q5GJ67	O75923
PDB IDs			4CAH 4CAI 4IHB 4IQH 7K6B 7KRB
Enriched GO Terms of Interacting Partners?
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