MYBL2 and CCNF

Number of citations of the paper that reports this interaction (PubMedID 25557911)
29

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		MYBL2	CCNF
Description		MYB proto-oncogene like 2	cyclin F
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Myb Complex	Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleus Cytoplasm Centrosome Centriole Cytosol SCF Ubiquitin Ligase Complex Cell Junction
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
	Biological Process	Mitotic Cell Cycle Regulation Of Transcription, DNA-templated Positive Regulation Of Neuron Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Mitotic Spindle Assembly Cellular Response To Leukemia Inhibitory Factor	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Re-entry Into Mitotic Cell Cycle Placenta Development Negative Regulation Of Centrosome Duplication Protein Ubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Mitotic Cell Cycle Phase Transition Cell Division
Pathways		Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 Polo-like kinase mediated events TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Fasting insulin ( 34059833) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Height ( 28552196) Triglyceride levels ( 32203549)
Interacting Genes		31 interacting genes: CCNA1 CCNA2 CCND1 CCNE1 CCNF CDC34 CDK2 CDK9 CREBBP CXCR4 E2F1 E2F3 EP300 LIN52 LIN9 LZTR1 MAP1LC3B MAPK6 NCOR1 NCOR2 PARP1 RBBP4 RBL1 SKP2 SND1 TRIM15 TTF2 UBB UBE2D4 ZBTB9 ZNF622	7 interacting genes: AKT1 CCNB1 CDC6 FZR1 MYBL2 RBPJ SCYL1
Entrez ID		4605	899
HPRD ID		03247	02574
Ensembl ID		ENSG00000101057	ENSG00000162063
Uniprot IDs		P10244	P41002 Q59HD0
PDB IDs		6C48
Enriched GO Terms of Interacting Partners?
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