MUSK and COLQ

Number of citations of the paper that reports this interaction (PubMedID 15159418)
47

Data Source:
HPRD (in vivo)

		MUSK	COLQ
Description		muscle associated receptor tyrosine kinase	collagen like tail subunit of asymmetric acetylcholinesterase
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane Neuromuscular Junction Receptor Complex Postsynaptic Membrane	Collagen Trimer Basement Membrane Extracellular Space Plasma Membrane Cell Junction Extracellular Matrix Neuromuscular Junction Synaptic Cleft Collagen-containing Extracellular Matrix
	Molecular Function	Protein Tyrosine Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Binding Collagen Binding ATP Binding Protein Tyrosine Kinase Collagen Receptor Activity Metal Ion Binding	Extracellular Matrix Structural Constituent Protein Binding Heparin Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organism Development Neuromuscular Junction Development Memory Regulation Of Synaptic Assembly At Neuromuscular Junction Positive Regulation Of Gene Expression Peptidyl-tyrosine Phosphorylation Cell Differentiation Positive Regulation Of Kinase Activity Collagen-activated Tyrosine Kinase Receptor Signaling Pathway Protein Autophosphorylation Skeletal Muscle Acetylcholine-gated Channel Clustering Positive Regulation Of Protein Geranylgeranylation	Acetylcholine Catabolic Process In Synaptic Cleft Regulation Of Synaptic Assembly At Neuromuscular Junction Extracellular Matrix Organization Skeletal Muscle Acetylcholine-gated Channel Clustering Establishment Of Protein Localization To Membrane
Pathways		ECM proteoglycans
Drugs		Fostamatinib
Diseases
GWAS		Body mass index ( 28552196) Heel bone mineral density ( 30598549) Metabolite levels ( 23823483) Orofacial cleft x maternal periconceptional smoking interaction (1df) ( 33937227) Plasma factor V levels in venous thrombosis (conditioned on rs6027) ( 31271701) Pulmonary function decline ( 22424883) Type 2 diabetes (dietary heme iron intake interaction) ( 23386860)	Diverticular disease ( 30177863 28585551) Diverticulitis ( 28585551)
Interacting Genes		7 interacting genes: COLQ DOK7 ERBIN ILKAP RAPSN STYX SYNE1	5 interacting genes: ACHE BCHE MRPS25 MUSK SGTB
Entrez ID		4593	8292
HPRD ID		03190	04328
Ensembl ID		ENSG00000030304	ENSG00000206561
Uniprot IDs		A0A087WSY1 O15146	Q9Y215
PDB IDs			1VZJ
Enriched GO Terms of Interacting Partners?
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