MT-ATP8 and PACSIN1

Number of citations of the paper that reports this interaction (PubMedID 20936779)
88

Data Source:
BioGRID (two hybrid)

		MT-ATP8	PACSIN1
Description		ATP synthase F0 subunit 8	protein kinase C and casein kinase substrate in neurons 1
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrial Proton-transporting ATP Synthase Complex, Coupling Factor F(o) Mitochondrial Inner Membrane Mitochondrial Proton-transporting ATP Synthase Complex Integral Component Of Membrane	Cytoplasm Endosome Cytosol Plasma Membrane COPI-coated Vesicle Cytoplasmic Vesicle Membrane Ruffle Membrane Axon Terminus Synapse Perinuclear Region Of Cytoplasm Photoreceptor Ribbon Synapse Presynaptic Endocytic Zone
	Molecular Function	Protein Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism	Protein Binding Phospholipid Binding Cytoskeletal Protein Binding Identical Protein Binding
	Biological Process	Mitochondrial ATP Synthesis Coupled Proton Transport	Cytoskeleton Organization Actin Filament Organization Regulation Of Endocytosis Negative Regulation Of Endocytosis Synaptic Vesicle Endocytosis Neuron Projection Morphogenesis Protein Localization To Membrane Protein Localization To Plasma Membrane Plasma Membrane Tubulation Positive Regulation Of Dendrite Development
Pathways		Formation of ATP by chemiosmotic coupling Cristae formation	Clathrin-mediated endocytosis
Drugs
Diseases
GWAS			Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 29273807 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Electrocardiographic traits (multivariate) ( 32602732) Free thyroxine concentration ( 30367059) High density lipoprotein cholesterol levels ( 30498476) Hip circumference adjusted for BMI ( 34021172) Inflammatory bowel disease ( 27569725) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 28552196)
Interacting Genes		4 interacting genes: GRB2 PACSIN1 RAPGEF2 WNK1	25 interacting genes: ANKRD24 ARHGAP17 DNM1 EHBP1 FTH1 GAS7 HTT ITCH JADE2 KAT7 KHDRBS1 MAPT MT-ATP8 PACSIN2 PACSIN3 PLEKHF2 POT1 RTKN2 SOS1 SPTBN1 SYNJ1 TPM4 TRPV4 WASF2 WASL
Entrez ID		4509	29993
HPRD ID			05936
Ensembl ID		ENSG00000228253	ENSG00000124507
Uniprot IDs		A0A1X7RCP4 P03928 U5YV54	Q5TZC3 Q9BY11
PDB IDs			3HAH 3HAI 3Q84 3QNI
Enriched GO Terms of Interacting Partners?
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