RNASEK and CYSLTR2

Number of citations of the paper that reports this interaction (PubMedID 28298427)
23

Data Source:
BioGRID (two hybrid)

		RNASEK	CYSLTR2
Description		ribonuclease K	cysteinyl leukotriene receptor 2
Image			No pdb structure
GO Annotations	Cellular Component	Cellular_component Integral Component Of Membrane	Cellular_component Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Endoribonuclease Activity Protein Binding	Cysteinyl Leukotriene Receptor Activity Leukotriene Receptor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding G Protein-coupled Peptide Receptor Activity
	Biological Process	RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	Immune Response Neuropeptide Signaling Pathway Regulation Of Catalytic Activity Leukotriene Signaling Pathway Cellular Response To Glucagon Stimulus
Pathways			Glucagon signaling in metabolic regulation Leukotriene receptors G alpha (q) signalling events G alpha (s) signalling events Glucagon-type ligand receptors ADORA2B mediated anti-inflammatory cytokines production LTC4-CYSLTR mediated IL4 production
Drugs			Nedocromil Leukotriene C4 Leukotriene D4
Diseases
GWAS			3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Post bronchodilator FEV1/FVC ratio ( 26634245) Response to inhaled corticosteroid treatment in asthma (change in FEV1) ( 24792382) Systemic juvenile idiopathic arthritis ( 27927641)
Interacting Genes		26 interacting genes: ARV1 ATP13A1 BNIP3 CYSLTR2 FIS1 FXYD6 GIMAP5 HMOX2 LRCH4 NINJ2 RTP2 SEC22A SERF1A SERF1B SERP2 SMAGP STX8 TAAR1 TIMM23 TMEM203 TMEM222 TMEM60 TREX1 VAPB VTI1B ZDHHC21	19 interacting genes: ATP5MC2 DBI ENO1 GNAS GRIK1 HSP90B1 KRTAP1-1 LNX1 MTUS2 NCKIPSD PCDH9 PCMT1 RNASEK RNF144A RTN4 SVOP TTC19 YIPF6 YWHAE
Entrez ID		440400	57105
HPRD ID		17568	09293
Ensembl ID		ENSG00000219200	ENSG00000152207
Uniprot IDs		Q6P5S7	A4ZKH2 Q5KU17 Q9NS75
PDB IDs		6WLW 6WM2 6WM3 6WM4
Enriched GO Terms of Interacting Partners?
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