MGST1 and TNFRSF10C

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MGST1	TNFRSF10C
Description		microsomal glutathione S-transferase 1	TNF receptor superfamily member 10c
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Outer Membrane Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane Azurophil Granule Membrane Apical Part Of Cell	Plasma Membrane Cell Surface Anchored Component Of Membrane
	Molecular Function	Glutathione Transferase Activity Glutathione Peroxidase Activity Protein Binding Identical Protein Binding Glutathione Binding	Transmembrane Signaling Receptor Activity Protein Binding TRAIL Binding
	Biological Process	Response To Xenobiotic Stimulus Response To Organonitrogen Compound Response To Lipopolysaccharide Leydig Cell Differentiation Glutathione Transport Cellular Response To Lipid Hydroperoxide Cellular Oxidant Detoxification	TRAIL-activated Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Process
Pathways		Glutathione conjugation Aflatoxin activation and detoxification Neutrophil degranulation	TP53 Regulates Transcription of Death Receptors and Ligands
Drugs		Glutathione Glutathione disulfide
Diseases
GWAS		Barrett's esophagus or Esophageal adenocarcinoma ( 32918910) Barrett's esophagus or esophageal adenocarcinoma x sex interaction (2df test) ( 32918910) Bell's palsy ( 33602968) Colorectal cancer (aspirin and/or NSAID use interaction) ( 25781442) Household income (MTAG) ( 31844048) Metabolite levels ( 23823483) Metastatic colorectal cancer survival in treatment with chemotherapy plus biologics ( 32958699) Visceral fat ( 22589738)	Basophil count ( 32888494) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Granulocyte count ( 27863252) Mean spheric corpuscular volume ( 32888494) Monocyte percentage of white cells ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Neutrophil percentage of granulocytes ( 27863252) Sum basophil neutrophil counts ( 27863252) Sum eosinophil basophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 32888494 27863252) White blood cell count (basophil) ( 27863252)
Interacting Genes		8 interacting genes: EGF FXYD3 FZD7 LTC4S NELFB SIGLEC12 TNFRSF10C VIP	34 interacting genes: APOA1 AQP6 ARL13B ASZ1 CD79A COQ9 CREB3L1 CXCL14 CYB5R3 DNAJC1 ERGIC3 FAM209A GPR152 GPR37L1 KCNJ6 KCNK5 LMNA LRSAM1 MGST1 MRPS18B PDZK1IP1 RAP1A RFLNB SGTA SLC27A6 SLC30A4 SRPK1 SRPK2 STOM SYAP1 TMEM45B TMEM80 TNFSF10 ZHX1
Entrez ID		4257	8794
HPRD ID		00705	04681
Ensembl ID		ENSG00000008394	ENSG00000173535
Uniprot IDs		A0A024RAX2 P10620	O14798
PDB IDs
Enriched GO Terms of Interacting Partners?
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