METTL1 and WDR4

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1103

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, two hybrid)
HPRD (two hybrid, in vivo)

		METTL1	WDR4
Description		methyltransferase 1, tRNA methylguanosine	WD repeat domain 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol TRNA Methyltransferase Complex	Nucleus Nucleoplasm Chromosome Cytosol TRNA Methyltransferase Complex
	Molecular Function	TRNA Binding Protein Binding TRNA (guanine-N7-)-methyltransferase Activity	Protein Binding TRNA (guanine-N7-)-methyltransferase Activity
	Biological Process	TRNA Modification TRNA Methylation RNA (guanine-N7)-methylation TRNA (guanine-N7)-methylation	TRNA Modification Cellular Response To DNA Damage Stimulus TRNA (guanine-N7)-methylation
Pathways		tRNA modification in the nucleus and cytosol	tRNA modification in the nucleus and cytosol
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Multiple sclerosis ( 19525955) Waist circumference adjusted for body mass index ( 34021172)	Blood and toenail selenium levels ( 25343990) Fasting plasma glucose ( 28270201)
Interacting Genes		3 interacting genes: AKT1 RPS6KA1 WDR4	6 interacting genes: FAM118A FEN1 METTL1 RABGGTB TERF1 TERF2
Entrez ID		4234	10785
HPRD ID		06834	09330
Ensembl ID		ENSG00000037897	ENSG00000160193
Uniprot IDs		Q9UBP6	P57081
PDB IDs		3CKK
Enriched GO Terms of Interacting Partners?
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