ARSA and POU1F1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ARSA	POU1F1
Description		arylsulfatase A	POU class 1 homeobox 1
Image
GO Annotations	Cellular Component	Extracellular Region Lysosome Endoplasmic Reticulum Lumen Azurophil Granule Lumen Lysosomal Lumen Extracellular Exosome	Chromatin Nucleus Nucleoplasm Cytosol
	Molecular Function	Arylsulfatase Activity Cerebroside-sulfatase Activity Calcium Ion Binding Protein Binding Sulfuric Ester Hydrolase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cell Population Proliferation Adenohypophysis Development Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Glycosphingolipid metabolism The activation of arylsulfatases Neutrophil degranulation
Drugs		4-Nitrocatechol sulfate 2-Amino-3-Hydroxy-3-Phosphonooxy-Propionic Acid
Diseases
GWAS		Aspartate aminotransferase levels ( 33547301) Blood metabolite levels ( 24816252) Fibrinogen ( 23969696) Fibrinogen levels ( 28107422) QT interval (ambient particulate matter interaction) ( 28749367) Urinary metabolite levels in chronic kidney disease ( 31959995) vWF and FVIII levels ( 30586737)	Menarche (age at onset) ( 25231870) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)
Interacting Genes		19 interacting genes: ANXA11 BMPR2 CAMK2B CCDC22 CETN2 CLEC4G CTSL CYB5R3 EID2B FOXI1 GAL3ST1 PKN1 POU1F1 PPIC PROP1 RHOXF2 SNCA TRIP13 VENTX	22 interacting genes: ARID5A ARSA CREBBP ETS1 GATA2 JUN KRTAP10-8 KRTAP15-1 KRTAP6-1 LASP1 LHX4 MSX2 NCOR1 NR1I2 NR1I3 NR3C1 PITX1 PPARA PPARG RAD54L2 UBE2I VDR
Entrez ID		410	5449
HPRD ID		09617	01409
Ensembl ID		ENSG00000100299	ENSG00000064835
Uniprot IDs		A0A0C4DFZ2 B4DVI5 P15289	P28069
PDB IDs		1AUK 1E1Z 1E2S 1E33 1E3C 1N2K 1N2L 2AIJ 2AIK 2HI8	5WC9
Enriched GO Terms of Interacting Partners?
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