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ARRB1 and BAG1
Number of citations of the paper that reports this interaction (PubMedID
21988832
)
87
Data Source:
BioGRID
(two hybrid)
ARRB1
BAG1
Description
arrestin beta 1
BAG cochaperone 1
Image
GO Annotations
Cellular Component
Golgi Membrane
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Lysosomal Membrane
Endosome
Cytosol
Plasma Membrane
Clathrin-coated Pit
Postsynaptic Density
Basolateral Plasma Membrane
Nuclear Body
Cytoplasmic Vesicle Membrane
Pseudopodium
Cytoplasmic Vesicle
Dendritic Spine
Postsynaptic Membrane
Nucleus
Cytoplasm
Cytosol
Membrane
Molecular Function
G Protein-coupled Receptor Binding
Transcription Coactivator Activity
Histone Acetyltransferase Activity
Enzyme Inhibitor Activity
GTPase Activator Activity
Insulin-like Growth Factor Receptor Binding
Protein Binding
Transcription Factor Binding
Estrogen Receptor Binding
Ubiquitin Protein Ligase Binding
Alpha-1A Adrenergic Receptor Binding
Alpha-1B Adrenergic Receptor Binding
Angiotensin Receptor Binding
Follicle-stimulating Hormone Receptor Binding
V2 Vasopressin Receptor Binding
AP-2 Adaptor Complex Binding
Clathrin Adaptor Activity
Transmembrane Transporter Binding
Protein Phosphorylated Amino Acid Binding
Arrestin Family Protein Binding
Adenyl-nucleotide Exchange Factor Activity
Protein Binding
Heat Shock Protein Binding
Ubiquitin Protein Ligase Binding
Chaperone Binding
Biological Process
Negative Regulation Of Protein Phosphorylation
Positive Regulation Of Protein Phosphorylation
G Protein-coupled Receptor Internalization
Positive Regulation Of Receptor Internalization
Regulation Of Transcription By RNA Polymerase II
Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Cell Population Proliferation
Response To Xenobiotic Stimulus
Protein Transport
Protein Ubiquitination
Negative Regulation Of Protein Ubiquitination
Positive Regulation Of Protein Ubiquitination
Negative Regulation Of NF-kappaB Transcription Factor Activity
Negative Regulation Of Interleukin-6 Production
Negative Regulation Of Interleukin-8 Production
Negative Regulation Of GTPase Activity
Positive Regulation Of Smooth Muscle Cell Apoptotic Process
Positive Regulation Of Rho Protein Signal Transduction
Positive Regulation Of Histone Acetylation
Follicle-stimulating Hormone Signaling Pathway
Stress Fiber Assembly
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Negative Regulation Of Neuron Apoptotic Process
Negative Regulation Of Notch Signaling Pathway
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of Histone H4 Acetylation
Apoptotic Process
Cell Surface Receptor Signaling Pathway
Negative Regulation Of Apoptotic Process
Regulation Of Catalytic Activity
Protein Stabilization
Chaperone Cofactor-dependent Protein Refolding
Pathways
Activated NOTCH1 Transmits Signal to the Nucleus
G alpha (s) signalling events
Lysosome Vesicle Biogenesis
Golgi Associated Vesicle Biogenesis
Thrombin signalling through proteinase activated receptors (PARs)
Activation of SMO
Activation of SMO
MAP2K and MAPK activation
Ub-specific processing proteases
Signaling by moderate kinase activity BRAF mutants
Signaling by high-kinase activity BRAF mutants
Signaling by BRAF and RAF1 fusions
Paradoxical activation of RAF signaling by kinase inactive BRAF
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
Signaling downstream of RAS mutants
Signaling by RAF1 mutants
Regulation of HSF1-mediated heat shock response
Drugs
(2R,3R,4S,5R)-2-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Diseases
GWAS
Obstructive sleep apnea trait (average respiratory event duration) (
26977737
)
Thiazide-induced adverse metabolic effects in hypertensive patients (
23400010
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Interacting Genes
55 interacting genes:
ADH6
ADRB1
ADRB2
AGTR1
AP2B1
ARF6
BAG1
BTK
C5AR1
CCR5
CDC42
CLTC
CRHR1
CSK
CXCR2
CYTH2
DVL1
DVL2
FGR
FLNA
GNMT
GPR50
GRK2
GSK3B
HCK
HCRTR1
JUN
LIMK1
MAP2K3
MAP2K4
MAPK1
MAPK10
MAPK3
MAPK9
MDM2
NEK6
NFKBIA
NSF
OPRD1
PDE4D
PIK3R2
POT1
POU2F1
PRDM16
PRKN
PTH1R
PTHLH
RALGDS
RPL15
SASH1
SLC9A5
SREBF2
STAM
TRHR
ZBTB43
29 interacting genes:
AR
ARRB1
BCL2
BCL2L1
ESR1
HBEGF
HSPA1A
HSPA1B
HSPA4
HSPA8
LRRK1
LRRK2
MAPT
MET
NR3C1
OGT
PDGFRB
PPP1R15A
PSMD1
PSMD2
PYGL
RAF1
RARA
RB1
SIAH1
STUB1
TRIM23
TRIM27
VDR
Entrez ID
408
573
HPRD ID
00146
03292
Ensembl ID
ENSG00000137486
ENSG00000107262
Uniprot IDs
B7Z1Q3
P49407
Q99933
PDB IDs
2IV8
6PWC
6TKO
6UP7
1HX1
1WXV
3FZF
3FZH
3FZK
3FZL
3FZM
3LDQ
3M3Z
5AQF
5AQG
5AQH
5AQI
5AQJ
5AQK
5AQL
5AQM
5AQN
5AQO
5AQP
5AQQ
5AQR
5AQS
5AQT
5AQU
5AQV
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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