MIR98 and EDC4

Number of citations of the paper that reports this interaction (PubMedID 28431233)
92

Data Source:
BioGRID (unspecified method)

		MIR98	EDC4
Description		microRNA 98	enhancer of mRNA decapping 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space	P-body Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	MRNA 3'-UTR Binding MRNA Binding Involved In Posttranscriptional Gene Silencing	Protein Binding
	Biological Process	Negative Regulation Of Cell Population Proliferation Negative Regulation Of Gene Expression Negative Regulation Of Extracellular Matrix Disassembly Negative Regulation Of Interleukin-1 Beta Production Negative Regulation Of Interleukin-10 Production Negative Regulation Of Interleukin-6 Production Negative Regulation Of Interleukin-8 Production Negative Regulation Of Tumor Necrosis Factor Production Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Negative Regulation Of Tyrosine Phosphorylation Of STAT Protein Positive Regulation Of Neuron Apoptotic Process Interleukin-6-mediated Signaling Pathway Negative Regulation Of Interleukin-6-mediated Signaling Pathway Regulation Of Cytokine Production Involved In Inflammatory Response Negative Regulation Of Cytokine Production Involved In Inflammatory Response Cellular Response To Amyloid-beta Negative Regulation Of Vascular Endothelial Cell Proliferation	Biological_process Deadenylation-independent Decapping Of Nuclear-transcribed MRNA
Pathways			mRNA decay by 5' to 3' exoribonuclease
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756)	HDL cholesterol ( 21347282) Metabolic syndrome ( 22399527) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		77 interacting genes: ADARB1 APOBEC3B ATXN2L C1QBP CPSF1 DARS1 DDX1 DDX21 DDX3X DDX3Y DHX36 EDC4 EIF2AK2 EPRS1 ESRP1 FAM98A FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI1 MSI2 NOL6 NONO NUDT16L1 NUFIP2 PDCD11 PLOD1 PTBP1 PTBP3 PUM1 QARS1 RARS1 RBM12B RBM14 RTCB SAFB SF3B1 SF3B2 SF3B3 SFPQ STRBP SYNCRIP TAF15 TRA2A TRA2B TRIM25 TUT4 U2SURP UPF1 YBX1 YBX3 ZFR ZNF346	41 interacting genes: CCL5 CDC42 EIF2AK2 FBLN1 FXR1 FXR2 GIT2 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR122 MIR128-2 MIR141 MIR15B MIR199A1 MIR200A MIR200B MIR200C MIR205 MIR20A MIR21 MIR214 MIR222 MIR29C MIR34A MIR34C MIR363 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A3 MIRLET7C MIRLET7D MIRLET7E PLA2G15 SUMO2 YTHDC1
Entrez ID		407054	23644
HPRD ID			06911
Ensembl ID		ENSG00000271886	ENSG00000038358
Uniprot IDs			Q6P2E9
PDB IDs
Enriched GO Terms of Interacting Partners?
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