MIR29C and LARS1

Number of citations of the paper that reports this interaction (PubMedID 28431233)
92

Data Source:
BioGRID (unspecified method)

		MIR29C	LARS1
Description		microRNA 29c	leucyl-tRNA synthetase 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Mitochondrion Extracellular Exosome Extracellular Vesicle	Cytoplasm Lysosome Endoplasmic Reticulum Cytosol Endomembrane System Nuclear Body Aminoacyl-tRNA Synthetase Multienzyme Complex
	Molecular Function	MRNA 3'-UTR Binding MRNA Binding Involved In Posttranscriptional Gene Silencing	Aminoacyl-tRNA Editing Activity Glutamine-tRNA Ligase Activity Leucine-tRNA Ligase Activity GTPase Activator Activity Protein Binding ATP Binding
	Biological Process	Negative Regulation Of Cell-matrix Adhesion Negative Regulation Of Cell Population Proliferation Negative Regulation Of Gene Expression Negative Regulation Of Angiogenesis Negative Regulation Of Cell Migration Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Positive Regulation Of Apoptotic Process Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of DNA Methylation Negative Regulation Of Protein Kinase B Signaling Negative Regulation Of Circulating Fibrinogen Levels Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Negative Regulation Of Amyloid-beta Formation Negative Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Negative Regulation Of Metalloendopeptidase Activity Negative Regulation Of Vascular Endothelial Cell Proliferation Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	TRNA Aminoacylation For Protein Translation Glutaminyl-tRNA Aminoacylation Leucyl-tRNA Aminoacylation Regulation Of Cell Size Positive Regulation Of TOR Signaling Cellular Response To Amino Acid Starvation Positive Regulation Of GTPase Activity Cellular Response To Amino Acid Stimulus Cellular Response To Leucine Aminoacyl-tRNA Metabolism Involved In Translational Fidelity Positive Regulation Of TORC1 Signaling Cellular Response To Leucine Starvation
Pathways			Selenoamino acid metabolism Cytosolic tRNA aminoacylation
Drugs			Leucine
Diseases
GWAS
Interacting Genes		87 interacting genes: ADARB1 AIMP1 APOBEC3B C1QBP CELF1 CELF2 CPSF7 DARS1 DDX1 DDX21 DDX3X DHX36 DZIP3 EDC4 EIF2AK2 EPRS1 ESRP1 FAM98A FUS G3BP2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LARS1 LIN28A LRPPRC MARS1 MATR3 MSI1 MSI2 MYEF2 NOL6 NONO NUDT21 PDCD11 PRMT1 PTBP1 PTBP3 PUF60 PUM1 PURA PURB QARS1 RARS1 RBFOX2 RBM14 RBM4 RTCA RTCB SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ STRBP SUGP2 SYNCRIP TAF15 TENT2 TIAL1 TRA2A TRA2B U2SURP UPF1 USP36 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346	55 interacting genes: CDC42 EEF1G ESR1 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR128-1 MIR128-2 MIR138-2 MIR15A MIR15B MIR17 MIR18A MIR18B MIR199A1 MIR19B1 MIR19B2 MIR200A MIR205 MIR206 MIR20B MIR21 MIR214 MIR221 MIR25 MIR29A MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR451A MIR7-1 MIR7-2 MIR9-1 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I SUMO2
Entrez ID		407026	51520
HPRD ID			01042
Ensembl ID		ENSG00000284214	ENSG00000133706
Uniprot IDs			A0A6I8PL42 B4DER1 B4E266 Q9P2J5
PDB IDs			2WFD 6KID 6KIE 6KQY 6KR7 6LPF 6LR6
Enriched GO Terms of Interacting Partners?
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