MIR20A and LIN28A

Number of citations of the paper that reports this interaction (PubMedID 28431233)
92

Data Source:
BioGRID (unspecified method)

		MIR20A	LIN28A
Description		microRNA 20a	lin-28 homolog A
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Extracellular Vesicle	P-body Nucleus Nucleolus Cytoplasm Rough Endoplasmic Reticulum Cytosol Polysome Cytoplasmic Stress Granule Ribonucleoprotein Complex
	Molecular Function	RNA Polymerase II Complex Binding MRNA 3'-UTR Binding MRNA Binding Involved In Posttranscriptional Gene Silencing	G-quadruplex RNA Binding RNA Binding Protein Binding Zinc Ion Binding Translation Initiation Factor Binding MiRNA Binding Polysome Binding Sequence-specific MRNA Binding
	Biological Process	Outflow Tract Morphogenesis Negative Regulation Of Protein Kinase Activity Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Gene Expression Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Positive Regulation Of BMP Signaling Pathway Negative Regulation Of BMP Signaling Pathway Negative Regulation Of Interleukin-17 Production Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Cellular Response To Vascular Endothelial Growth Factor Stimulus Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Osteoblast Differentiation Positive Regulation Of Angiogenesis Negative Regulation Of Inflammatory Response Positive Regulation Of Phagocytosis Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Protein Kinase B Signaling Negative Regulation Of Cell Adhesion Molecule Production Cellular Response To Lipopolysaccharide Negative Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Negative Regulation Of Sprouting Angiogenesis Negative Regulation Of P38MAPK Cascade Negative Regulation Of Vascular Endothelial Growth Factor Production Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Positive Regulation Of Vascular Associated Smooth Muscle Cell Migration Negative Regulation Of Cardioblast Proliferation Positive Regulation Of Pulmonary Blood Vessel Remodeling	Germ Cell Development MiRNA Catabolic Process Negative Regulation Of Translation Stem Cell Population Maintenance Pre-miRNA Processing RNA 3'-end Processing Positive Regulation Of TOR Signaling Positive Regulation Of Neuron Differentiation Negative Regulation Of Glial Cell Differentiation Stem Cell Differentiation Positive Regulation Of Protein Kinase B Signaling RNA 3' Uridylation Cellular Response To Glucose Stimulus Positive Regulation Of Cell Proliferation Involved In Kidney Development Positive Regulation Of Production Of MiRNAs Involved In Gene Silencing By MiRNA Positive Regulation Of Cytoplasmic Translation
Pathways			Transcriptional regulation of pluripotent stem cells
Drugs
Diseases
GWAS			Caffeine consumption from tea ( 33287642) Glucose homeostasis traits ( 25524916) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494)
Interacting Genes		73 interacting genes: AIMP2 APOBEC3B C1QBP CRTAP DARS1 DDX1 DDX21 DDX3X DDX3Y DHX36 DZIP3 EDC4 EIF2AK2 EPRS1 ERAL1 FAM98A FUS HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP3 KARS1 KNOP1 LARP7 LIN28A LRPPRC LSM10 LSM11 MARS1 MATR3 MSI1 MSI2 MYEF2 NOL6 NONO NUDT21 PDCD11 PLOD1 PRMT1 PTBP1 PTBP3 PUF60 PUM1 RARS1 RBM14 RBM4 RTCB SF3B1 SF3B2 SF3B3 SFPQ SUGP2 SYNCRIP TAF15 TIAL1 TRA2A TRA2B UPF1 UTP20 YBX1 YBX3 ZNF346	72 interacting genes: MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I ZDHHC17 ZNF275
Entrez ID		406982	79727
HPRD ID			17278
Ensembl ID		ENSG00000283762	ENSG00000131914
Uniprot IDs			Q9H9Z2
PDB IDs			2CQF 2LI8 5UDZ
Enriched GO Terms of Interacting Partners?
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