MIR145 and NUDT16L1

Number of citations of the paper that reports this interaction (PubMedID 28431233)
92

Data Source:
BioGRID (unspecified method)

		MIR145	NUDT16L1
Description		microRNA 145	nudix hydrolase 16 like 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Exosome	Nucleus
	Molecular Function	RNA Polymerase II Complex Binding MRNA 3'-UTR Binding MRNA Binding Involved In Posttranscriptional Gene Silencing	RNA Binding Protein Binding SnoRNA Binding Protein Homodimerization Activity M7G(5')pppN Diphosphatase Activity Nucleotide Phosphatase Activity, Acting On Free Nucleotides Phosphodiesterase Decapping Endonuclease Activity
	Biological Process	Regulation Of Smooth Muscle Contraction Negative Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Ectodermal Cell Differentiation Positive Regulation Of Fibroblast Migration Negative Regulation Of Angiogenesis Actin Cytoskeleton Organization Negative Regulation Of Cell Migration Negative Regulation Of Interleukin-16 Production Positive Regulation Of Interleukin-10 Production Regulation Of Collagen Biosynthetic Process Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Vascular Associated Smooth Muscle Cell Differentiation Myofibroblast Differentiation Angiotensin-activated Signaling Pathway Positive Regulation Of Macrophage Activation Establishment Or Maintenance Of Cell Type Involved In Phenotypic Switching Positive Regulation Of Macrophage Differentiation Mesodermal Cell Differentiation Negative Regulation Of Smooth Muscle Cell Proliferation Negative Regulation Of Inflammatory Response Negative Regulation Of Protein Kinase B Signaling Aorta Smooth Muscle Tissue Morphogenesis Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Canonical Wnt Signaling Pathway Regulation Of Phenotypic Switching Negative Regulation Of Somatic Stem Cell Population Maintenance Negative Regulation Of Somatic Stem Cell Division Negative Regulation Of Vascular Associated Smooth Muscle Cell Dedifferentiation Positive Regulation Of Cardiac Vascular Smooth Muscle Cell Differentiation	MRNA Catabolic Process Sno(s)RNA Catabolic Process Negative Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Pathways
Drugs
Diseases
GWAS
Interacting Genes		79 interacting genes: ADARB1 APOBEC3B AQR C1QBP DARS1 DDX1 DDX21 DDX3X DHX36 EIF2AK2 EPRS1 ERAL1 FAM98A FUS G3BP2 HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP6 LARP7 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 NONO NUDT16L1 NUDT21 PDCD11 PGAM5 PRMT1 PTBP1 PTBP3 PUF60 PUM1 RARS1 RBM14 RBM4 RTCA RTCB SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SYNCRIP TAF15 TENT2 TIAL1 TRA2A TRA2B U2SURP UPF1 UTP20 YBX1 YBX3 ZFR ZNF346	52 interacting genes: APP CABP2 ERBB2 FBXO7 HNRNPF HNRNPH1 IKZF3 INCA1 KRT31 LRRK1 METTL17 MIR122 MIR128-1 MIR128-2 MIR138-1 MIR141 MIR145 MIR18B MIR200C MIR21 MIR25 MIR31 MIR34A MIR34B MIR363 MIR451A MIR7-3 MIR9-1 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NEDD4L NEK6 NTAQ1 PNMA1 RECK SMARCD1 TRAF2 TRAF4 TRAF7 TRIM68 ZRANB1
Entrez ID		406937	84309
HPRD ID			15309
Ensembl ID		ENSG00000276365	ENSG00000168101
Uniprot IDs			B2RD96 Q9BRJ7 W4VSQ8
PDB IDs			3KVH 5ZCJ 6CO1 6D0L
Enriched GO Terms of Interacting Partners?
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