MIR122 and EDC4

Number of citations of the paper that reports this interaction (PubMedID 28431233)
92

Data Source:
BioGRID (unspecified method)

		MIR122	EDC4
Description		microRNA 122	enhancer of mRNA decapping 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Extracellular Exosome Extracellular Vesicle	P-body Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Cytoplasmic Ribonucleoprotein Granule
	Molecular Function		Protein Binding
	Biological Process	Gene Silencing By MiRNA	Biological_process Deadenylation-independent Decapping Of Nuclear-transcribed MRNA
Pathways			mRNA decay by 5' to 3' exoribonuclease
Drugs
Diseases
GWAS		Gamma glutamyl transferase levels ( 29403010 33339817) High density lipoprotein cholesterol levels ( 29083408) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (alkaline phosphatase) ( 33972514) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Platelet count ( 32888494) Plateletcrit ( 32888494) Serum alkaline phosphatase levels ( 33339817)	HDL cholesterol ( 21347282) Metabolic syndrome ( 22399527) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		70 interacting genes: AIMP1 AIMP2 C1QBP CPSF1 DARS1 DDX1 DDX21 DDX3X DHX37 EDC4 EIF2AK2 EPRS1 ERAL1 FUS HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LIN28A LIN28B LRPPRC MARS1 MATR3 NOL6 NONO NUDT16L1 NUDT21 PDCD11 PLOD1 PRMT1 PTBP1 PTBP3 PUF60 PURA QARS1 RARS1 RBFOX2 RBM14 RTCA RTCB SF3A1 SF3B1 SF3B2 SF3B3 SFPQ STRBP SYNCRIP TAF15 TENT2 TRA2A TRA2B UPF1 UTP20 YBX1 YBX3 ZNF346	41 interacting genes: CCL5 CDC42 EIF2AK2 FBLN1 FXR1 FXR2 GIT2 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR122 MIR128-2 MIR141 MIR15B MIR199A1 MIR200A MIR200B MIR200C MIR205 MIR20A MIR21 MIR214 MIR222 MIR29C MIR34A MIR34C MIR363 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A3 MIRLET7C MIRLET7D MIRLET7E PLA2G15 SUMO2 YTHDC1
Entrez ID		406906	23644
HPRD ID			06911
Ensembl ID		ENSG00000284440	ENSG00000038358
Uniprot IDs			Q6P2E9
PDB IDs
Enriched GO Terms of Interacting Partners?
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