LSS and TMEM167B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

		LSS	TMEM167B
Description		lanosterol synthase	transmembrane protein 167B
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Lipid Droplet Membrane	Golgi Membrane Golgi Apparatus Integral Component Of Membrane
	Molecular Function	Lanosterol Synthase Activity Protein Binding Beta-amyrin Synthase Activity	Molecular_function Protein Binding
	Biological Process	Steroid Biosynthetic Process Cholesterol Biosynthetic Process Triterpenoid Biosynthetic Process Regulation Of Protein Stability	Constitutive Secretory Pathway
Pathways		Cholesterol biosynthesis Activation of gene expression by SREBF (SREBP)
Drugs		R048-8071 Lanosterol
Diseases
GWAS		White blood cell count ( 27863252)	Apolipoprotein B levels ( 32203549) Liver enzyme levels (alkaline phosphatase) ( 33972514) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		12 interacting genes: AQP6 CIB1 GPR35 MX2 NR4A1 NUP214 SIRT5 SLC10A1 SLC10A6 TMEM167B TMEM86B YIF1A	33 interacting genes: ACKR2 AGPAT3 APOL3 AQP10 AQP6 ASPH C14orf180 CD300C CD47 CTXN3 EBP FXYD6-FXYD2 HSD17B11 HSD17B13 LETMD1 LSS MFSD14B MGST2 PLLP REEP4 SACM1L SEC22B SERINC2 SLC34A3 SMPD2 STX12 STX1B TAS2R19 TM4SF19 TMEM100 TMEM107 UNC50 ZDHHC21
Entrez ID		4047	56900
HPRD ID		02945	16474
Ensembl ID		ENSG00000160285	ENSG00000215717
Uniprot IDs		B2R694 P48449	A0A024R096 A0A494C0V7 Q9NRX6
PDB IDs		1W6J 1W6K
Enriched GO Terms of Interacting Partners?
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