C4orf3 and GPR61

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		C4orf3	GPR61
Description		chromosome 4 open reading frame 3	G protein-coupled receptor 61
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane	Endosome Plasma Membrane Endosome Membrane Integral Component Of Membrane Receptor Complex
	Molecular Function		G Protein-coupled Receptor Activity Protein Binding Arrestin Family Protein Binding
	Biological Process	Negative Regulation Of Calcium Ion Binding Negative Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity	G Protein-coupled Receptor Signaling Pathway Positive Regulation Of CAMP-mediated Signaling
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 28240269)	Adult body size ( 32376654) Body mass index ( 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Body size at age 10 ( 32376654) Childhood body mass index ( 26604143) Chronotype ( 30696823) Hepcidin/ferritin ratio ( 27846281) Morning person ( 30696823) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction (3df) ( 34099189) Stearic acid (18:0) levels ( 23362303) Waist circumference ( 25673412)
Interacting Genes		67 interacting genes: ADGRG3 AQP2 AQP6 ARL13B BCL2L13 BIK C5AR2 CALM1 CCRL2 CD79A CISD2 CLDN9 CREB3L1 CXCR2 CYBC1 DEGS1 EBP ERGIC3 FAM174A FAM209A FFAR2 GJA5 GJB4 GJB5 GLP1R GPR61 HHATL HTR2C JAGN1 LAPTM5 LMNA LY6G6C MFSD14B MILR1 MMD MMGT1 MRM3 MS4A3 NCAPH2 PLEKHO1 PTGES REEP4 RETREG3 RHBDL1 RHCG SERINC2 SHISAL1 SLC14A2 SLC19A3 SLC35C2 SLC35E3 SLC39A2 SLC41A3 SLCO3A1 SMO SSMEM1 STX1A SYNPR TIMMDC1 TM4SF19 TMEM101 TMEM237 TMEM248 TMEM45A TMEM45B TMEM51 YIF1A	20 interacting genes: APP ARL6IP6 ATP6V0B C4orf3 CLDND1 CTXN3 EMP3 FCER1G GJA8 GJB6 KLRC1 PLP1 PMP22 SCN3B SLC12A7 SLC13A4 STRIT1 TMEM147 TMEM218 TRARG1
Entrez ID		401152	83873
HPRD ID		14223	06077
Ensembl ID		ENSG00000164096	ENSG00000156097
Uniprot IDs		Q8WVX3	G4XH66 Q9BZJ8
PDB IDs
Enriched GO Terms of Interacting Partners?
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