SERTM1 and LRRC4C

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SERTM1	LRRC4C
Description		serine rich and transmembrane domain containing 1	leucine rich repeat containing 4C
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Extracellular Space Plasma Membrane Membrane Integral Component Of Membrane Schaffer Collateral - CA1 Synapse Glutamatergic Synapse Integral Component Of Postsynaptic Density Membrane
	Molecular Function	Protein Binding	Protein Binding Cell Adhesion Molecule Binding Cell-cell Adhesion Mediator Activity
	Biological Process		Regulation Of Axonogenesis Modulation Of Chemical Synaptic Transmission Synaptic Membrane Adhesion
Pathways
Drugs
Diseases
GWAS		Cocaine dependence ( 31212010) Nickel levels ( 26025379) Urinary albumin excretion ( 32277301)	Blood protein levels ( 30072576) Cerebellum cortex volume ( 31530798) Cerebrospinal fluid beta-site APP cleaving enzyme levels ( 29751835) Cerebrospinal fluid p-tau levels ( 29274321) Diastolic blood pressure response to thiazide and thiazide-like diuretics in hypertension ( 31754133) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) General risk tolerance (MTAG) ( 30643258) High myopia ( 31816047) Iris color (L* coordinate) ( 30895295) Mastocytosis (KIT D816V positive) ( 33421400) Mosquito bite size ( 28199695) Myopia ( 27182965) Osteoporosis-related phenotypes ( 20548944) Pediatric central nervous system tumors (early onset)(pleiotropy) ( 33226468) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245) Refractive error ( 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking status (ever vs never smokers) ( 30643258) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Survival in colorectal cancer ( 26586795) Temperament (bipolar disorder) ( 22365631)
Interacting Genes		15 interacting genes: APP CD53 CLDN7 EMP1 FREM2 GJB1 GPR42 GPX8 KCNJ6 LHFPL5 LRRC4C MS4A4A MTIF3 SPACA1 TMEM19	29 interacting genes: AGTRAP BDKRB1 BMP10 BRICD5 CLDN19 CLEC1A CLEC4G CMTM5 CREB3L4 DOLK DRAM1 EMP3 GJB2 LEPROTL1 LHFPL5 MIP NTNG1 PGAP2 PLP2 SERTM1 SMIM1 SNAP47 STX5 TRAF6 TWSG1 VEZT VSTM1 WHRN YIPF6
Entrez ID		400120	57689
HPRD ID		14219	12303
Ensembl ID		ENSG00000180440	ENSG00000148948
Uniprot IDs		A2A2V5	Q4JIV9 Q4JIW0 Q9HCJ2
PDB IDs			3ZYJ
Enriched GO Terms of Interacting Partners?
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