ARL1 and GCC2

Number of citations of the paper that reports this interaction (PubMedID 12972563)
53

Data Source:
BioGRID (two hybrid)

		ARL1	GCC2
Description		ADP ribosylation factor like GTPase 1	GRIP and coiled-coil domain containing 2
Image
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Trans-Golgi Network Cytosol Trans-Golgi Network Membrane	Nucleoplasm Golgi Apparatus Trans-Golgi Network Cytosol Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding Enzyme Activator Activity Protein Domain Specific Binding Metal Ion Binding	Protein Binding Small GTPase Binding Identical Protein Binding
	Biological Process	Intracellular Protein Transport Golgi Organization Toxin Metabolic Process Vesicle-mediated Transport Activation Of Phospholipase D Activity Protein Localization To Golgi Apparatus Retrograde Transport, Endosome To Golgi Golgi Vesicle Transport	Protein Targeting To Lysosome Microtubule Organizing Center Organization Protein Localization To Golgi Apparatus Microtubule Anchoring Late Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Golgi To Plasma Membrane Protein Transport Regulation Of Protein Exit From Endoplasmic Reticulum Recycling Endosome To Golgi Transport Golgi Ribbon Formation
Pathways		Retrograde transport at the Trans-Golgi-Network	Retrograde transport at the Trans-Golgi-Network Signaling by ALK fusions and activated point mutants
Drugs		Guanosine-5'-Diphosphate
Diseases
GWAS		Lung cancer in never smokers ( 28604730) Response to methotrexate in juvenile idiopathic arthritis ( 24709693)	Excessive hairiness ( 29895819) Eyebrow thickness ( 26926045) Liver enzyme levels (alkaline phosphatase) ( 33972514) Low density lipoprotein cholesterol levels ( 32154731) Mean platelet volume ( 27863252) Platelet distribution width ( 32888494)
Interacting Genes		8 interacting genes: ARFIP2 COPG2 DRD2 GCC1 GCC2 GOLGA1 GOLGA4 SCOC	7 interacting genes: ARL1 ICAM3 POU2AF1 RANBP2 SPOP SRPK2 SULT1C3
Entrez ID		400	9648
HPRD ID		04574	11001
Ensembl ID		ENSG00000120805	ENSG00000135968
Uniprot IDs		B4DZG7 P40616	B3KR21 Q8IWJ2
PDB IDs		1UPT 4DCN 5EE5 5J5C	3BBP
Enriched GO Terms of Interacting Partners?
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