RHOH and MBLAC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RHOH	MBLAC1
Description		ras homolog family member H	metallo-beta-lactamase domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Immunological Synapse Cytoplasm Cytoskeleton Plasma Membrane Cell Cortex Cytoplasmic Vesicle Cell Projection
	Molecular Function	GTPase Activity GTPase Inhibitor Activity Protein Binding GTP Binding Kinase Inhibitor Activity Protein Kinase Binding Small GTPase Binding	Hydrolase Activity Metal Ion Binding
	Biological Process	Regulation Of Transcription, DNA-templated Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Motor Neuron Axon Guidance Regulation Of Cell Shape Rac Protein Signal Transduction Cell Projection Assembly T Cell Differentiation Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Negative Regulation Of Catalytic Activity Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Engulfment Of Apoptotic Cell Mast Cell Activation Positive Regulation Of T Cell Differentiation Regulation Of Neutrophil Migration
Pathways		RHOH GTPase cycle
Drugs
Diseases
GWAS		Graves' disease ( 21841780) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244) Pre-treatment viral load in HIV-1 infection ( 31219150)	Brain morphology (MOSTest) ( 32665545) Coronary artery disease ( 29212778) Hematocrit ( 32888494) Hemoglobin levels ( 32327693) Microalbuminuria in type 1 diabetes ( 31537649) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		24 interacting genes: ARHGDIA ARHGDIB ARHGDIG BANP CCNH FAM90A1 GDI1 IQUB ITGB1BP1 KANK2 KCNH2 LRIF1 MBLAC1 MTX2 PLEKHA7 RIPPLY1 SCNM1 SORL1 SUOX TCF19 TGFBR1 TMEM33 UTP14A XPNPEP1	11 interacting genes: AGR2 C10orf55 FNDC8 INCA1 MYOZ2 NDUFAB1 POGZ RHOH TRAF2 TRIP13 VAC14
Entrez ID		399	255374
HPRD ID		03616	18584
Ensembl ID		ENSG00000168421	ENSG00000214309
Uniprot IDs		Q15669 Q6ICP4	A4D2B0
PDB IDs			4V0H
Enriched GO Terms of Interacting Partners?
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