Description |
LCK proto-oncogene, Src family tyrosine kinase |
erb-b2 receptor tyrosine kinase 4 |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
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Interacting Genes |
147 interacting genes:
ACP1
ADAM15
AJUBA
AR
ARHGAP17
ASB9
AXL
BCAR1
BRCA1
C1QTNF2
CAMK1D
CBL
CCR5
CD2
CD247
CD28
CD38
CD3E
CD4
CD44
CD48
CD5
CD55
CD79A
CD79B
CD8A
CDC25C
CDC42
CDC45
CDKAL1
CITED4
CSF2RB
CSF3R
CSK
CSNK2B
CTDSP1
CTLA4
CTNND2
DAPP1
DEF6
DLG1
DOK1
DOK2
DOK3
EGFR
ERBB2
ERBB3
ERBB4
ESR1
ESR2
EZR
FAM166B
FAM174A
FAS
FASLG
FCGR3A
FYN
G3BP1
GAB2
GATA3
GRAP
HSP90AA1
IFNAR1
IKBKG
IL2RB
ITK
JAK3
KHDRBS1
KIR2DL3
KIT
LAT
LAX1
LCP2
LIME1
LZTS2
MAPK1
MAPK3
MAPT
MED28
MET
MS4A1
MUC1
NCDN
NEDD9
NFKBIA
NFKBID
NOTCH1
NR3C1
PAG1
PAK2
PECAM1
PI4KA
PIK3CA
PIK3R1
PLCG1
PLCG2
PLD2
PRKACA
PRKCA
PRKCD
PRKCQ
PTK2
PTK2B
PTPN11
PTPN22
PTPN6
PTPRC
PTPRF
PTPRH
PXN
RAF1
RASA1
RIN3
RORB
SH2B3
SH2D1A
SH2D2A
SH3BP2
SHC1
SIT1
SKAP1
SKAP2
SMAD2
SMAD3
SMURF1
SOCS1
SOS1
SQSTM1
STAT1
STAT3
STAT5A
SYK
THY1
TRAT1
TRIM35
TRPV4
TUB
UBAP2
UBE3A
UHRF2
UNC119
VAV1
WAS
WASL
YBX1
ZAP70
ZSCAN20
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152 interacting genes:
ABL1
ABL2
ADAM17
ALDOA
ANKS1A
ANKS1B
BCAR3
BLK
BMPR2
BTC
CASP10
CASP8
CCN2
CD44
CDC25C
CFL1
CRK
DLG1
DLG2
DLG3
DLG4
DUSP10
DUSP14
DUSP16
DUSP18
DUSP19
DUSP21
DUSP6
EGFR
ERBB2
ERBB3
EREG
ERG28
FAM241B
FES
FGR
FKBP1A
GABARAPL2
GRAP2
GRB10
GRB2
GRB7
HBEGF
HCK
HDAC6
HSH2D
ILKAP
INPPL1
IRF2BP2
ITCH
ITK
LCK
LCP2
LRRC7
LYN
MATK
MTMR2
MTMR6
MTMR9
MUC1
MUC4
NCK1
NCK2
NEDD4
NRG1
NRG2
NRG3
NRG4
NTRK2
PIK3R1
PIK3R2
PIK3R3
PIN4
PLCG1
PLCG2
PPM1A
PPM1B
PPM1F
PRDX5
PRRG4
PTK6
PTPDC1
PTPN11
PTPN12
PTPN20
PTPN21
PTPN6
PTPN7
PTPRH
PTPRR
PTPRT
RASA1
RNF41
RTN4
S100A11
SELENOK
SH2B1
SH2B2
SH2B3
SH2D1A
SH2D1B
SH2D2A
SH2D3C
SH3BP2
SHB
SHC1
SHC2
SHC3
SHC4
SHD
SLA
SLA2
SMIM20
SNAP91
SNTB2
SOCS1
SOCS2
SOCS3
SOCS5
SOCS6
SRC
STAP1
STAT5A
STAT5B
STYX
SYK
SYNM
TAB1
TAB2
TEC
TFAP2C
TGFA
TMA7
TMEM134
TMEM14A
TMEM230
TNS1
TNS2
TNS3
TNS4
TRO
TVP23B
TXK
TXN
VAV1
VAV2
VAV3
WWOX
YAP1
YES1
ZAP70
ZNF532
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Entrez ID |
3932 |
2066 |
HPRD ID |
01080 |
02767 |
Ensembl ID |
ENSG00000182866
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ENSG00000178568
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Uniprot IDs |
A0A0S2Z3Y4
A0A0S2Z3Y8
P06239
Q573B4
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Q15303
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PDB IDs |
1BHF
1BHH
1CWD
1CWE
1FBZ
1H92
1IJR
1KIK
1LCJ
1LCK
1LKK
1LKL
1Q68
1Q69
1QPC
1QPD
1QPE
1QPJ
1X27
2IIM
2OF2
2OF4
2OFU
2OFV
2OG8
2PL0
2ZM1
2ZM4
2ZYB
3AC1
3AC2
3AC3
3AC4
3AC5
3AC8
3ACJ
3ACK
3AD4
3AD5
3AD6
3B2W
3BRH
3BYM
3BYO
3BYS
3BYU
3KMM
3KXZ
3LCK
3MPM
4C3F
4D8K
5MTM
5MTN
6H6A
6PDJ
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2AHX
2L2T
2LCX
2R4B
3BBT
3BBW
3BCE
3U2P
3U7U
3U9U
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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