LAMC2 and LAMB3

Number of citations of the paper that reports this interaction (PubMedID 10964684)
3

Data Source:
HPRD (in vivo)

		LAMC2	LAMB3
Description		laminin subunit gamma 2	laminin subunit beta 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Laminin-2 Complex Extracellular Space Cell Cortex Membrane Perinuclear Region Of Cytoplasm Collagen-containing Extracellular Matrix	Extracellular Region Laminin-5 Complex Laminin Complex Collagen-containing Extracellular Matrix
	Molecular Function	Signaling Receptor Binding Extracellular Matrix Structural Constituent Heparin Binding	Structural Molecule Activity Extracellular Matrix Structural Constituent Protein Binding Protein-containing Complex Binding
	Biological Process	Cell Adhesion Motor Neuron Axon Guidance Positive Regulation Of Cell Population Proliferation Epidermis Development Animal Organ Morphogenesis Tissue Development Dendrite Development Positive Regulation Of Cell Migration	Epidermis Development Animal Organ Morphogenesis Tissue Development Cell Migration Substrate Adhesion-dependent Cell Spreading Endodermal Cell Differentiation Brown Fat Cell Differentiation Basement Membrane Assembly
Pathways		Degradation of the extracellular matrix Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures Anchoring fibril formation Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions Type I hemidesmosome assembly MET activates PTK2 signaling	Degradation of the extracellular matrix Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures Anchoring fibril formation Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions Type I hemidesmosome assembly MET activates PTK2 signaling
Drugs
Diseases
GWAS		Acne (severe) ( 30542056) Blood protein levels ( 30072576 29875488) Clozapine-induced agranulocytosis ( 25187353) HDL cholesterol ( 21347282) Low density lipoprotein cholesterol levels ( 32154731) Morning person ( 30696823) Systemic lupus erythematosus ( 21408207)	Fentanyl consumption in laparoscopic-assisted colectomy (first 24 hours) ( 26566055)
Interacting Genes		8 interacting genes: BMP1 COL7A1 CSF1R FBLN2 LAMB3 NID1 SCAP SLA2	6 interacting genes: BMP1 COL7A1 LAMA3 LAMC2 MDFI THBS1
Entrez ID		3918	3914
HPRD ID		01031	01032
Ensembl ID		ENSG00000058085	ENSG00000196878
Uniprot IDs		Q13753	A0A0S2Z3R6 Q13751
PDB IDs
Enriched GO Terms of Interacting Partners?
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