LAMA3 and BMP1

Number of citations of the paper that reports this interaction (PubMedID 10806203)
46

Data Source:
HPRD (in vitro, in vivo)

		LAMA3	BMP1
Description		laminin subunit alpha 3	bone morphogenetic protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Laminin-5 Complex Endoplasmic Reticulum Collagen-containing Extracellular Matrix Extracellular Exosome	Extracellular Region Extracellular Space Golgi Apparatus Vesicle
	Molecular Function	Integrin Binding Structural Molecule Activity Extracellular Matrix Structural Constituent	Metalloendopeptidase Activity Serine-type Endopeptidase Activity Cytokine Activity Calcium Ion Binding Protein Binding Growth Factor Activity Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Identical Protein Binding
	Biological Process	Morphogenesis Of A Polarized Epithelium Integrin-mediated Signaling Pathway Axon Guidance Epidermis Development Animal Organ Morphogenesis Tissue Development Cell Migration Regulation Of Cell Adhesion Regulation Of Cell Migration Endodermal Cell Differentiation Regulation Of Embryonic Development Cell-cell Adhesion	Skeletal System Development Cartilage Condensation Ossification Proteolysis Signal Transduction Multicellular Organism Development Cell Differentiation Collagen Fibril Organization Positive Regulation Of Cartilage Development
Pathways		Degradation of the extracellular matrix Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures Anchoring fibril formation Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions ECM proteoglycans Type I hemidesmosome assembly MET activates PTK2 signaling	Degradation of the extracellular matrix Degradation of the extracellular matrix Collagen biosynthesis and modifying enzymes Anchoring fibril formation Crosslinking of collagen fibrils
Drugs		Lanoteplase
Diseases
GWAS		Allergic rhinitis ( 25085501) Amyotrophic lateral sclerosis ( 22959728) Composite immunoglobulin trait (IgA x IgG/IgM) ( 28628107) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252)	Coronary artery disease ( 29212778) Hypertriglyceridemia ( 23505323) Myocardial infarction ( 33532862) Waist-to-hip ratio adjusted for BMI ( 28552196)
Interacting Genes		7 interacting genes: APC BMP1 LAMB3 PLAT PLG SDC2 SLC35E1	18 interacting genes: ADRA1A CHRD CLIP2 COL1A1 COL5A1 COL5A2 COL7A1 CST7 DST GEM HSPG2 LAMA3 LAMB3 LAMC2 PTPRZ1 TP53 TWSG1 YLPM1
Entrez ID		3909	649
HPRD ID		02883	00209
Ensembl ID		ENSG00000053747	ENSG00000168487
Uniprot IDs		A0A0A0MSA0 A0A0A0MTS5 A0A0A6YYF2 Q16787	P13497
PDB IDs			3EDG 3EDH 6BSL 6BSM 6BTN 6BTO 6BTP 6BTQ
Enriched GO Terms of Interacting Partners?
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