L1CAM and CNTN2

Number of citations of the paper that reports this interaction (PubMedID 12139915)
23

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		L1CAM	CNTN2
Description		L1 cell adhesion molecule	contactin 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Focal Adhesion Cell Surface Integral Component Of Membrane Axon Dendrite Neuronal Cell Body Axonal Growth Cone Collagen-containing Extracellular Matrix	Plasma Membrane Cell Surface Axon Node Of Ranvier Neuronal Cell Body Myelin Sheath Juxtaparanode Region Of Axon Synapse Anchored Component Of Postsynaptic Membrane
	Molecular Function	Protein Binding Axon Guidance Receptor Activity Protein Domain Specific Binding	Protein Binding Carbohydrate Binding Identical Protein Binding Protein Self-association Cell-cell Adhesion Mediator Activity
	Biological Process	Chemotaxis Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Cell-matrix Adhesion Nervous System Development Axon Guidance Cell Migration Neuron Projection Development Positive Regulation Of Axon Extension Synapse Organization Axon Development	Microtubule Cytoskeleton Organization Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Axon Guidance Axonal Fasciculation Learning Adult Walking Behavior Regulation Of Cell Morphogenesis Involved In Differentiation Positive Regulation Of Protein Processing Cerebral Cortex GABAergic Interneuron Migration Central Nervous System Myelination Regulation Of Axon Diameter Receptor Internalization Clustering Of Voltage-gated Potassium Channels Negative Regulation Of Neuron Differentiation Regulation Of Neuronal Synaptic Plasticity Regulation Of Astrocyte Differentiation Positive Regulation Of Adenosine Receptor Signaling Pathway Dendrite Self-avoidance Protein Localization To Juxtaparanode Region Of Axon Establishment Of Protein Localization To Juxtaparanode Region Of Axon Presynaptic Membrane Organization
Pathways		Basigin interactions L1CAM interactions L1CAM interactions Recycling pathway of L1 Recycling pathway of L1 Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins Signal transduction by L1	L1CAM interactions NCAM1 interactions NrCAM interactions
Drugs		Ethanol
Diseases
GWAS			Adventurousness ( 30643258) Aspartate aminotransferase levels ( 33547301) Blood protein levels ( 30072576 29875488 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) HDL cholesterol levels ( 32203549) Mean platelet volume ( 24026423) Meat-related diet ( 32066663) Number of sexual partners ( 30643258) Periodontitis (stage III/IV grade C) ( 33745150) Red blood cell count ( 27863252) Schizophrenia ( 30285260) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		24 interacting genes: ANK1 ANK2 CNTN1 CNTN2 CSNK2A1 EZR FGFR1 ITGA5 ITGAV LINC00839 MSN NCAM1 NCAN NRP1 NRP2 NUMB PEA15 PLXNA1 PLXNB1 PRNP RANBP9 RDX RPS6KA1 RPS6KA2	13 interacting genes: CDK4 CHEK1 CNTN1 CNTNAP2 EGFR L1CAM NCAN NEK2 NFYB NRCAM TUBG1 UBE4B VAC14
Entrez ID		3897	6900
HPRD ID		02394	01826
Ensembl ID		ENSG00000198910	ENSG00000184144
Uniprot IDs		P32004	A1L3A3 A1ML24 Q02246
PDB IDs			2OM5
Enriched GO Terms of Interacting Partners?
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