BLOC1S3 and BLOC1S2

Number of citations of the paper that reports this interaction (PubMedID 15102850)
115

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		BLOC1S3	BLOC1S2
Description		biogenesis of lysosomal organelles complex 1 subunit 3	biogenesis of lysosomal organelles complex 1 subunit 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Transport Vesicle BLOC-1 Complex Axon Cytoplasm	Gamma-tubulin Complex Mitochondrion Lysosomal Membrane BLOC-1 Complex BORC Complex Axon Cytoplasm
	Molecular Function	Molecular_function Protein Binding Protein Transmembrane Transporter Activity	Protein Binding Gamma-tubulin Binding
	Biological Process	Eye Development Anterograde Axonal Transport Response To Xenobiotic Stimulus Platelet Activation Neuron Projection Development Melanosome Transport Melanosome Organization Positive Regulation Of Natural Killer Cell Activation Secretion Of Lysosomal Enzymes Endosome To Melanosome Transport Pigmentation Anterograde Synaptic Vesicle Transport Platelet Dense Granule Organization Protein Transmembrane Transport	Anterograde Axonal Transport Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Endosomal Transport Neuron Projection Development Lysosome Localization Melanosome Organization Anterograde Synaptic Vesicle Transport Platelet Dense Granule Organization Mitochondrial Outer Membrane Permeabilization
Pathways		Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Quantitative traits ( 19197348)	Refractive error ( 32231278)
Interacting Genes		3 interacting genes: BLOC1S1 BLOC1S2 DTNBP1	35 interacting genes: APP ARFIP2 BFSP2 BLOC1S1 BLOC1S3 BLOC1S4 BLOC1S5 BLOC1S6 C8orf33 CCDC146 CCHCR1 CCNC CTNNA3 DCTN2 ERP27 EXOC8 FAM161B FAM9B GADD45G GEM HMOX2 KRT26 MEST P4HA3 PAM16 PICK1 RDH11 SH2D4A SNAPIN SSC5D STX2 TNNT1 TRIML2 WASHC1 WASHC3
Entrez ID		388552	282991
HPRD ID		12527	12526
Ensembl ID		ENSG00000189114	ENSG00000196072
Uniprot IDs		Q6QNY0	A0A087X1N6 F1T0F0 Q6QNY1
PDB IDs
Enriched GO Terms of Interacting Partners?
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