CLEC12B and LSMEM2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CLEC12B	LSMEM2
Description		C-type lectin domain family 12 member B	leucine rich single-pass membrane protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	External Side Of Plasma Membrane Integral Component Of Membrane Protein-containing Complex	Integral Component Of Membrane
	Molecular Function	Protein Phosphatase Binding Carbohydrate Binding Signaling Receptor Inhibitor Activity	Protein Binding
	Biological Process	Natural Killer Cell Inhibitory Signaling Pathway Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Negative Regulation Of Signaling Receptor Activity
Pathways
Drugs
Diseases
GWAS		Malaria ( 31844061) Sensory disturbances after bilateral sagittal split ramus osteotomy ( 23834954) Systolic blood pressure in sickle cell anemia ( 24058526)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Depressive symptom (appetite changes) (binary trait) ( 31530331) Depressive symptoms (binary sum-score) ( 31530331) Depressive symptoms (sum-score) ( 31530331) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		11 interacting genes: IL1RL1 JAGN1 LPAR3 LSMEM2 MALL OPRM1 PLLP PMP22 SCD SEC22A VMA21	20 interacting genes: APP CD72 CLDN7 CLEC12B CTXN3 CXCL9 EMP1 GIMAP5 KLRC1 LSMEM1 PLN SEC22A SFTPC SGTA SMIM3 SPACA1 SPG21 STX7 TMEM143 TMEM218
Entrez ID		387837	132228
HPRD ID		18266	08789
Ensembl ID		ENSG00000256660	ENSG00000179564
Uniprot IDs		A0A140VK10 Q2HXU8	Q8N112
PDB IDs
Enriched GO Terms of Interacting Partners?
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