CLEC2A and CLEC2D

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CLEC2A	CLEC2D
Description		C-type lectin domain family 2 member A	C-type lectin domain family 2 member D
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GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane
	Molecular Function	Protein Binding Carbohydrate Binding Protein Homodimerization Activity	Transmembrane Signaling Receptor Activity Carbohydrate Binding Natural Killer Cell Lectin-like Receptor Binding
	Biological Process	Natural Killer Cell Mediated Cytotoxicity	Cell Surface Receptor Signaling Pathway
Pathways			Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Malaria ( 31844061)	Autoimmune thyroid disease ( 32581359) HDL cholesterol levels x short total sleep time interaction (1df test) ( 31719535) HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Multiple sclerosis ( 31604244)
Interacting Genes		5 interacting genes: CLEC2D GPR37L1 GPX8 HIBADH TEX29	33 interacting genes: - ADIPOQ ATP6V0C B3GALT5 BRICD5 CD68 CLDN19 CLDN2 CLEC2A CLRN2 CXCL9 DEFB121 ENTPD8 ERMP1 FAM3C FNDC9 GPR42 IL1RL1 KLRB1 KLRC1 LEPROTL1 NKG7 PLLP PLN PLP1 RPRM SEC22A SHMT2 SYT15 TM4SF18 TMEM190 TMEM80 TSPAN4
Entrez ID		387836	29121
HPRD ID		16720	16134
Ensembl ID		ENSG00000188393	ENSG00000069493
Uniprot IDs		Q6UVW9	Q9UHP7 W8JXM2
PDB IDs		4IOP	4QKG 4QKH 4QKI 4QKJ 4WCO 5MGT
Enriched GO Terms of Interacting Partners?
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