KRT1 and IVL

Number of citations of the paper that reports this interaction (PubMedID 8999895)
30

Data Source:
BioGRID (pull down)

		KRT1	IVL
Description		keratin 1	involucrin
Image
GO Annotations	Cellular Component	Cornified Envelope Extracellular Region Extracellular Space Nucleus Cytosol Cytoskeleton Membrane Keratin Filament Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle Ficolin-1-rich Granule Lumen	Cornified Envelope Cytoplasm Centrosome Cytosol Nuclear Body Extracellular Exosome
	Molecular Function	Protein Binding Carbohydrate Binding Structural Constituent Of Skin Epidermis Signaling Receptor Activity Protein Heterodimerization Activity	Protein Binding
	Biological Process	Complement Activation, Lectin Pathway Retina Homeostasis Response To Oxidative Stress Peptide Cross-linking Fibrinolysis Regulation Of Angiogenesis Negative Regulation Of Inflammatory Response Protein Heterotetramerization Establishment Of Skin Barrier	Response To UV-B Peptide Cross-linking Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Keratinocyte Differentiation Keratinization
Pathways		Neutrophil degranulation Keratinization Formation of the cornified envelope	Formation of the cornified envelope
Drugs		Zinc Copper Zinc acetate
Diseases
GWAS			Asthma ( 31619474) Vitamin D levels ( 26704534)
Interacting Genes		54 interacting genes: - AMOTL2 CALB2 CSTA DSP EVPL F12 FANCA FANCC FFAR2 GOLGA2 GOLGA6L9 HAUS1 HMG20A HOOK2 IVL KNG1 KRT13 KRT14 KRT15 KRT16 KRT19 KRT24 KRT25 KRT26 KRT27 KRT28 KRT31 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT5 KRT6A LINC00839 LORICRIN MBL2 NINL NUP62 OGT PDE4DIP PI3 PRKCE RINT1 SGTB TFIP11 TLCD4 TRIM54 U2AF1 UBE3A YWHAQ	11 interacting genes: ACD CSTA DNAH3 DSP EVPL IL6R KRT1 LORICRIN POT1 SPRR3 UCHL5
Entrez ID		3848	3713
HPRD ID		00763	00931
Ensembl ID		ENSG00000167768	ENSG00000163207
Uniprot IDs		P04264	P07476
PDB IDs		4ZRY 6E2J 6UUI	1EU0
Enriched GO Terms of Interacting Partners?
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