KPNA5 and DCPS

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KPNA5	DCPS
Description		karyopherin subunit alpha 5	decapping enzyme, scavenger
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	P-body Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol
	Molecular Function	Protein Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity	RNA 7-methylguanosine Cap Binding Exoribonuclease Activity Protein Binding Identical Protein Binding M7G(5')pppN Diphosphatase Activity
	Biological Process	NLS-bearing Protein Import Into Nucleus	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Cellular Response To Menadione Negative Regulation Of Programmed Cell Death Exonucleolytic Catabolism Of Deadenylated MRNA MRNA Cis Splicing, Via Spliceosome RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Pathways		ISG15 antiviral mechanism NS1 Mediated Effects on Host Pathways	mRNA decay by 3' to 5' exoribonuclease
Drugs			7-methyl-GpppA 7-methyl-7,8-dihydroguanosine-5'-diphosphate 7-methyl-5'-guanylic acid 7-methyl-guanosine-5'-triphosphate-5'-guanosine 5-{[1-(2-fluorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamine 5-{[1-(2,3-dichlorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamine 5-[(1S)-1-(3-chlorophenyl)ethoxy]quinazoline-2,4-diamine
Diseases
GWAS		Early cardiac repolarization ( 31600170) Telomere length ( 21460395)	Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Lymphocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494 27863252)
Interacting Genes		28 interacting genes: ANP32A ANP32B ARNT BRMS1 CDKN1B DCPS EPAS1 FAM214B FBXO7 HIF1A HNRNPC IL32 KAT5 LMNB1 MLH1 NMNAT1 NRF1 NUP50 POLR3C POU6F2 RAD52 RBBP4 SPOP SPOPL TSEN54 TWIST1 WT1 ZNF326	10 interacting genes: CDC20 CDC27 CHST4 CSNK2A2 FZR1 GPC5 KPNA2 KPNA5 KPNA6 YWHAQ
Entrez ID		3841	28960
HPRD ID		05179	16787
Ensembl ID		ENSG00000196911	ENSG00000110063
Uniprot IDs		O15131	A0A384MTI8 Q96C86
PDB IDs		4U2X	1ST0 1ST4 1XML 1XMM 3BL7 3BL9 3BLA 4QDE 4QDV 4QEB 5OSY
Enriched GO Terms of Interacting Partners?
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