KCNJ8 and TMEM140

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KCNJ8	TMEM140
Description		potassium inwardly rectifying channel subfamily J member 8	transmembrane protein 140
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Plasma Membrane Voltage-gated Potassium Channel Complex Inward Rectifying Potassium Channel Myofibril Potassium Ion-transporting ATPase Complex Sarcolemma	Integral Component Of Membrane
	Molecular Function	Inward Rectifier Potassium Channel Activity Protein Binding ATP Binding ATP-activated Inward Rectifier Potassium Channel Activity Sulfonylurea Receptor Binding ATPase-coupled Cation Transmembrane Transporter Activity Voltage-gated Potassium Channel Activity Involved In Ventricular Cardiac Muscle Cell Action Potential Repolarization	Protein Binding
	Biological Process	Kidney Development Potassium Ion Transport Heart Development Response To Lipopolysaccharide Regulation Of Ion Transmembrane Transport Response To Exogenous DsRNA Defense Response To Virus Potassium Ion Transmembrane Transport Inorganic Cation Transmembrane Transport Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential Transport Across Blood-brain Barrier Potassium Ion Import Across Plasma Membrane
Pathways		ATP sensitive Potassium channels
Drugs		Phenformin Levosimendan Glyburide Thiamylal Gliquidone Glisoxepide Yohimbine Butamben
Diseases
GWAS		Birth weight ( 31043758)
Interacting Genes		7 interacting genes: ABCC8 ABCC9 EMD KCNJ11 KCNJ2 TMEM140 TMEM54	50 interacting genes: APH1A AQP6 ASGR2 CD22 CD53 CD79A CGRRF1 CLDN5 CLDN7 CLEC17A CLRN1 CREB3 EBP FAM209A FAM210B FCER1G FNDC9 GOLM1 GPR152 GPR42 HHLA2 HSD17B13 IFNGR2 KCNJ8 KRTAP10-8 LMNA LY6E MFF MGST3 MILR1 MS4A3 MSMO1 PDZK1IP1 PSCA RMDN3 SCN3B SHISAL1 SIT1 SLC39A9 SPACA1 STOM SYNE4 TEX29 TMEM182 TMEM205 TMEM207 TMEM9 TMX2 TSPAN12 TSPO2
Entrez ID		3764	55281
HPRD ID		02962	07723
Ensembl ID		ENSG00000121361	ENSG00000146859
Uniprot IDs		A0A024RAV6 Q15842	Q9NV12
PDB IDs
Enriched GO Terms of Interacting Partners?
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