KCNJ3 and GPD2

		KCNJ3	GPD2
Description		potassium inwardly rectifying channel subfamily J member 3	glycerol-3-phosphate dehydrogenase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex External Side Of Plasma Membrane T-tubule Parallel Fiber To Purkinje Cell Synapse Integral Component Of Presynaptic Membrane	Mitochondrion Mitochondrial Inner Membrane Glycerol-3-phosphate Dehydrogenase Complex
	Molecular Function	Inward Rectifier Potassium Channel Activity Protein Binding G-protein Activated Inward Rectifier Potassium Channel Activity Voltage-gated Potassium Channel Activity Involved In Atrial Cardiac Muscle Cell Action Potential Repolarization Voltage-gated Potassium Channel Activity Involved In Ventricular Cardiac Muscle Cell Action Potential Repolarization	Glycerol-3-phosphate Dehydrogenase (quinone) Activity Calcium Ion Binding Sn-glycerol-3-phosphate:ubiquinone-8 Oxidoreductase Activity
	Biological Process	Potassium Ion Transport Regulation Of Ion Transmembrane Transport Response To Electrical Stimulus Regulation Of Heart Rate By Cardiac Conduction Membrane Repolarization During Atrial Cardiac Muscle Cell Action Potential Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential Ventricular Cardiac Muscle Cell Membrane Repolarization Potassium Ion Import Across Plasma Membrane	Glycerol-3-phosphate Metabolic Process Glycerophosphate Shuttle Glycerol Catabolic Process
Pathways		Activation of G protein gated Potassium channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	Synthesis of PA Triglyceride catabolism
Drugs		Atomoxetine Ethanol Halothane B-nonylglucoside Dronedarone Ifenprodil
Diseases
GWAS		Age at voice drop ( 27182965) Alcoholic chronic pancreatitis ( 28754779) Automobile speeding propensity ( 30643258) Dentures ( 31235808) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Feeling miserable ( 29500382) General cognitive ability ( 29844566) Leisure-time exercise behaviour ( 30102679) Leisure-time exercise behaviour (age-stratified) ( 30102679) Lung function (FEV1/FVC) ( 30061609) Metabolite levels ( 23823483) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Risk-taking tendency (4-domain principal component model) ( 30643258) Rosacea symptom severity ( 29771307) Smoking initiation ( 30617275 33082346) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Systemic lupus erythematosus ( 24871463)	Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Depression ( 29700475) Diisocyanate-induced asthma ( 25918132) Familial squamous cell lung carcinoma ( 29924316) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Motion sickness ( 25628336) Myopia ( 27182965) Possible neuropathic pain in post total joint replacement surgery for osteoarthritis ( 28051079) Refractive error ( 32231278) Response to statin therapy ( 20339536) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Ulcerative colitis ( 25082827) Urinary albumin-to-creatinine ratio ( 31630189)
Interacting Genes		6 interacting genes: GNB1 GPD2 KCNJ5 KCNJ6 KCNJ9 NFATC3	8 interacting genes: ALDOA CHCHD7 GALNT5 IFIH1 KCNJ3 RAB3IP SLC25A12 TPRG1L
Entrez ID		3760	2820
HPRD ID		03323	00715
Ensembl ID		ENSG00000162989	ENSG00000115159
Uniprot IDs		D2X9V0 D2XBF0 P48549	P43304 Q53T76
PDB IDs
Enriched GO Terms of Interacting Partners?
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